Microbiome-based therapeutics

MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …

Probiotics in medicine: a long debate

E Stavropoulou, E Bezirtzoglou - Frontiers in immunology, 2020 - frontiersin.org
During the last years probiotics gained the attention of clinicians for their use in the
prevention and treatment of multiple diseases. Probiotics main mechanisms of action …

Gut microbiota and colonization resistance against bacterial enteric infection

QR Ducarmon, RD Zwittink, BVH Hornung… - Microbiology and …, 2019 - Am Soc Microbiol
The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …

The human intestinal microbiome in health and disease

SV Lynch, O Pedersen - New England journal of medicine, 2016 - Mass Medical Soc
The Human Intestinal Microbiome in Health and Disease | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

The intestinal microbiota: antibiotics, colonization resistance, and enteric pathogens

S Kim, A Covington, EG Pamer - Immunological reviews, 2017 - Wiley Online Library
The human gastrointestinal tract hosts a diverse network of microorganisms, collectively
known as the microbiota that plays an important role in health and disease. For instance, the …

[HTML][HTML] Necrotic enteritis in broiler chickens: disease characteristics and prevention using organic antibiotic alternatives–a comprehensive review

ME Abd El-Hack, MT El-Saadony, AR Elbestawy… - Poultry science, 2022 - Elsevier
In line with the substantial increase in the broiler industry worldwide, Clostridium perfringens-
induced necrotic enteritis (NE) became a continuous challenge leading to high economic …

Mechanisms and consequences of intestinal dysbiosis

GA Weiss, T Hennet - Cellular and Molecular Life Sciences, 2017 - Springer
The composition of the gut microbiota is in constant flow under the influence of factors such
as the diet, ingested drugs, the intestinal mucosa, the immune system, and the microbiota …

Clostridium difficile infection

WK Smits, D Lyras, DB Lacy, MH Wilcox… - Nature reviews Disease …, 2016 - nature.com
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

[HTML][HTML] Cognitive impairment by antibiotic-induced gut dysbiosis: analysis of gut microbiota-brain communication

EE Fröhlich, A Farzi, R Mayerhofer… - Brain, behavior, and …, 2016 - Elsevier
Emerging evidence indicates that disruption of the gut microbial community (dysbiosis)
impairs mental health. Germ-free mice and antibiotic-induced gut dysbiosis are two …

Clostridium difficile colitis: pathogenesis and host defence

MC Abt, PT McKenney, EG Pamer - Nature Reviews Microbiology, 2016 - nature.com
Clostridium difficile is a major cause of intestinal infection and diarrhoea in individuals
following antibiotic treatment. Recent studies have begun to elucidate the mechanisms that …