G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions
C Esnault, T Magat, A Zine El Aabidine… - Nature …, 2023 - nature.com
Metazoan promoters are enriched in secondary DNA structure-forming motifs, such as G-
quadruplexes (G4s). Here we describe 'G4access', an approach to isolate and sequence …
quadruplexes (G4s). Here we describe 'G4access', an approach to isolate and sequence …
Comprehensive mapping of genetic variation at Epromoters reveals pleiotropic association with multiple disease traits
J Wan, A van Ouwerkerk, JC Mouren… - Nucleic Acids …, 2024 - academic.oup.com
There is growing evidence that a wide range of human diseases and physiological traits are
influenced by genetic variation of cis-regulatory elements. We and others have shown that a …
influenced by genetic variation of cis-regulatory elements. We and others have shown that a …
[HTML][HTML] Untargeted CUT&Tag and BG4 CUT&Tag are both enriched at G-quadruplexes and accessible chromatin
M Thompson, A Byrd - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
G-quadruplex DNA structures (G4s) form within single-stranded DNA in nucleosome-free
chromatin. As G4s modulate gene expression and genomic stability, genome-wide mapping …
chromatin. As G4s modulate gene expression and genomic stability, genome-wide mapping …