Myelodysplastic syndromes
SD Nimer - Blood, The Journal of the American Society of …, 2008 - ashpublications.org
There has been a remarkable explosion of knowledge into the molecular defects that
underlie the acute and chronic leukemias, leading to the introduction of targeted therapies …
underlie the acute and chronic leukemias, leading to the introduction of targeted therapies …
[HTML][HTML] Diagnosis and treatment of chronic myelomonocytic leukemias in adults: recommendations from the European Hematology Association and the European …
R Itzykson, P Fenaux, D Bowen, NCP Cross… - …, 2018 - journals.lww.com
Chronic myelomonocytic leukemia (CMML) is a disease of the elderly, and by far the most
frequent overlap myelodysplastic/myeloproliferative neoplasm in adults. Aside from the …
frequent overlap myelodysplastic/myeloproliferative neoplasm in adults. Aside from the …
New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients
D Haase, U Germing, J Schanz… - Blood, The Journal …, 2007 - ashpublications.org
We have generated a large, unique database that includes morphologic, clinical,
cytogenetic, and follow-up data from 2124 patients with myelodysplastic syndromes (MDSs) …
cytogenetic, and follow-up data from 2124 patients with myelodysplastic syndromes (MDSs) …
[HTML][HTML] Cytogenetic risk stratification in chronic myelomonocytic leukemia
E Such, J Cervera, D Costa, F Solé, T Vallespí… - …, 2011 - ncbi.nlm.nih.gov
Background The prognostic value of cytogenetic findings in chronic myelomonocytic
leukemia is unclear. Our purpose was to evaluate the independent prognostic impact of …
leukemia is unclear. Our purpose was to evaluate the independent prognostic impact of …
Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML
Using metaphase cytogenetics (MC), chromosomal abnormalities are found in only a
proportion of patients with myelodysplastic syndrome (MDS). We hypothesized that with new …
proportion of patients with myelodysplastic syndrome (MDS). We hypothesized that with new …
Genetic abnormalities and pathophysiology of MDS
N Hosono - International journal of clinical oncology, 2019 - Springer
Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid malignancies
characterized by peripheral blood cytopenia and dishematopoiesis and frequently progress …
characterized by peripheral blood cytopenia and dishematopoiesis and frequently progress …
Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia
JP Maciejewski, A Risitano, EM Sloand… - Blood, The Journal …, 2002 - ashpublications.org
A serious complication of aplastic anemia (AA) is its evolution to clonal hematologic
diseases such as myelodysplasia (MDS) and leukemia, which is usually associated with the …
diseases such as myelodysplasia (MDS) and leukemia, which is usually associated with the …
Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes
BACKGROUND AND OBJECTIVES: The main prognostic factors in myelodysplastic
syndromes (MDS) are chromosomal abnormalities, the proportion of blasts in bone marrow …
syndromes (MDS) are chromosomal abnormalities, the proportion of blasts in bone marrow …
Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q− syndrome patients
A Pellagatti, M Jädersten… - Proceedings of the …, 2007 - National Acad Sciences
Myelodysplastic syndromes (MDSs) are a group of hematopoietic stem cell disorders
characterized by ineffective hematopoiesis and peripheral blood cytopenias. Lenalidomide …
characterized by ineffective hematopoiesis and peripheral blood cytopenias. Lenalidomide …
The myelodysplastic syndromes: diagnosis and treatment
DP Steensma, JM Bennett - Mayo Clinic Proceedings, 2006 - Elsevier
The myelodysplastic syndromes (MDSs) are common, acquired, clinically challenging
hematologic conditions that are characterized by bone marrow failure and a risk of …
hematologic conditions that are characterized by bone marrow failure and a risk of …