Coagulopathy and haemorrhagic progression in traumatic brain injury: advances in mechanisms, diagnosis, and management

M Maegele, H Schöchl, T Menovsky… - The Lancet …, 2017 - thelancet.com
Normal haemostasis depends on an intricate balance between mechanisms of bleeding and
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …

The coagulopathy of trauma: a review of mechanisms

JR Hess, K Brohi, RP Dutton, CJ Hauser… - Journal of Trauma …, 2008 - journals.lww.com
Background: Bleeding is the most frequent cause of preventable death after severe injury.
Coagulopathy associated with severe injury complicates the control of bleeding and is …

Hemorrhagic progression of a contusion after traumatic brain injury: a review

D Kurland, C Hong, B Aarabi, V Gerzanich… - Journal of …, 2012 - liebertpub.com
The magnitude of damage to cerebral tissues following head trauma is determined by the
primary injury, caused by the kinetic energy delivered at the time of impact, plus numerous …

The controversial second impact syndrome: a review of the literature

LA McLendon, SF Kralik, PA Grayson, MR Golomb - Pediatric neurology, 2016 - Elsevier
Background Second impact syndrome is a devastating injury that primarily affects athletic
children and young adults. It occurs when a second concussion occurs before symptoms …

Coagulopathy in severe traumatic brain injury: a prospective study

P Talving, R Benfield, P Hadjizacharia… - Journal of Trauma …, 2009 - journals.lww.com
Background: The incidence and risk factors for traumatic brain injury (TBI)-associated
coagulopathy after severe TBI (sTBI) and the effect of this complication on outcomes have …

Acute traumatic coagulopathy in the setting of isolated traumatic brain injury: a systematic review and meta-analysis

DS Epstein, B Mitra, G O'Reilly, JV Rosenfeld… - Injury, 2014 - Elsevier
Background and objectives Acute traumatic coagulopathy (ATC) has been reported in the
setting of isolated traumatic brain injury (iTBI) and associated with high mortality and poor …

Prevalence and impact of abnormal ROTEM® assays in severe blunt trauma: results of the 'Diagnosis and Treatment of Trauma-Induced Coagulopathy (DIA-TRE-TIC …

H Tauber, P Innerhofer, R Breitkopf… - British journal of …, 2011 - academic.oup.com
Abstract Background ROTEM®/TEG®(rotational thromboelastometry) assays appear to be
useful for the treatment of bleeding trauma patients. However, data on the prevalence and …

Acute coagulopathy in isolated blunt traumatic brain injury

A Wafaisade, R Lefering, T Tjardes, S Wutzler… - Neurocritical care, 2010 - Springer
Background The role of acute coagulopathy after traumatic brain injury (TBI) on outcome has
gained increasing appreciation over the recent years. This study was conducted to assess …

Time course of coagulopathy in isolated severe traumatic brain injury

T Lustenberger, P Talving, L Kobayashi, K Inaba… - Injury, 2010 - Elsevier
BACKGROUND: Time aspects of coagulopathy following severe traumatic brain injury (sTBI)
are ill defined throughout the literature. Thus, the aim of this study was to evaluate the time …

Acute and delayed mild coagulopathy are related to outcome in patients with isolated traumatic brain injury

S Greuters, A van den Berg, G Franschman… - Critical care, 2011 - Springer
Introduction The relationship between isolated traumatic brain injury (TBI) associated
coagulopathy and patient prognosis frequently lacks information regarding the time course …