Cross-kingdom lipid transfer in arbuscular mycorrhiza symbiosis and beyond

A Keymer, C Gutjahr - current opinion in plant biology, 2018 - Elsevier
Highlights•Arbuscular mycorrhiza fungi are likely fatty acid auxotrophs.•Plants maintain an
arbuscular mycorrhiza (AM)-specific lipid biosynthesis pathway.•Independent experimental …

High CO2 levels drive the TCA cycle backwards towards autotrophy

L Steffens, E Pettinato, TM Steiner, A Mall, S König… - Nature, 2021 - nature.com
It has recently been shown that in anaerobic microorganisms the tricarboxylic acid (TCA)
cycle, including the seemingly irreversible citrate synthase reaction, can be reversed and …

[HTML][HTML] Lipid transfer from plants to arbuscular mycorrhiza fungi

A Keymer, P Pimprikar, V Wewer, C Huber, M Brands… - elife, 2017 - elifesciences.org
Arbuscular mycorrhiza (AM) symbioses contribute to global carbon cycles as plant hosts
divert up to 20% of photosynthate to the obligate biotrophic fungi. Previous studies …

Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis

Z Ahmed - Progress in molecular biology and translational …, 2022 - Elsevier
Precision medicine is driven by the paradigm shift of empowering clinicians to predict the
most appropriate course of action for patients with complex diseases and to improve routine …

[HTML][HTML] Practicing precision medicine with intelligently integrative clinical and multi-omics data analysis

Z Ahmed - Human genomics, 2020 - Springer
Precision medicine aims to empower clinicians to predict the most appropriate course of
action for patients with complex diseases like cancer, diabetes, cardiomyopathy, and COVID …

Human gene and disease associations for clinical‐genomics and precision medicine research

Z Ahmed, S Zeeshan, D Mendhe… - Clinical and translational …, 2020 - Wiley Online Library
We are entering the era of personalized medicine in which an individual's genetic makeup
will eventually determine how a doctor can tailor his or her therapy. Therefore, it is becoming …

Two-step electrochemical reduction of CO2 towards multi-carbon products at high current densities

NSR Cuellar, C Scherer, B Kaçkar, W Eisenreich… - Journal of CO2 …, 2020 - Elsevier
Two-step electrochemical reduction of CO 2 is investigated as an alternative to increase
selectivity towards C 2 and C 3 products. In this type of proposed cascade electrocatalytic …

Applications of artificial intelligence multiomics in precision oncology

R Srivastava - Journal of cancer research and clinical oncology, 2023 - Springer
Cancer is the second leading worldwide disease that depends on oncogenic mutations and
non-mutated genes for survival. Recent advancements in next-generation sequencing …

Multi-omics strategies for personalized and predictive medicine: past, current, and future translational opportunities

Z Ahmed - Emerging topics in life sciences, 2022 - portlandpress.com
Precision medicine is driven by the paradigm shift of empowering clinicians to predict the
most appropriate course of action for patients with complex diseases and improve routine …

[HTML][HTML] Conversion of Hyperpolarized [1-13C]Pyruvate in Breast Cancer Cells Depends on Their Malignancy, Metabolic Program and Nutrient Microenvironment

M Grashei, P Biechl, F Schilling, AM Otto - Cancers, 2022 - mdpi.com
Simple Summary The metabolic phenotype of cancer cells depends on their metabolic
program and the availability of nutrients in the tumor microenvironment. Metabolic activities …