Importance Prostate cancer, a leading cause of cancer death among men, urgently requires
new prevention strategies, which may involve targeting men with an underlying genetic …

Prostate cancer (PrCa) is a largely heritable and polygenic disease. It is the most common
cancer in people with prostates (PwPs) in Europe and the USA, including in PwPs of African …

Despite advances in screening, diagnosis, and treatment for prostate cancer (PCa), Black
men tend to be diagnosed at younger ages, have higher mortality rates, and are at …

The relationship between tissue-specific DNA methylation and cancer risk remains
inadequately elucidated. Leveraging resources from the Genotype-Tissue Expression …

Recent advancement in genome‐wide association studies (GWAS) comes from not only
increasingly larger sample sizes but also the shift in focus towards underrepresented …

Simple Summary From a scientific perspective, we are beginning to comprehend the
evolution of cancer better, but much remains unknown. The quantity of medications has …

Abstract Background African American (AA) men have the highest incidence and mortality
rates of prostate cancer (PCa) among all racial groups in the United States. While race is a …

Background: Glucagon-like peptide-1 receptor (GLP1R) agonists have been approved by
Food and Drug Administration for management of obesity. However, the causal relationship …

Background Recent advances in the detection and treatment of prostate cancer (PCa) have
reduced morbidity and mortality from this common cancer. Despite these improvements …

Genetic and epigenetic alterations are cancer hallmark characteristics. However, the role of
inherited cancer predisposition alleles in co‐opting lineage factor epigenetic reprogramming …