Genomic-based precision medicine has not only improved tumour therapy but has also
shown its weaknesses. Genomic profiling and mutation analysis have identified alterations …

Myxofibrosarcoma (MFS) is one of the most common adult soft tissue sarcomas, typically
arising in the extremities. Histologically, MFS is classified into three grades: low …

Immunotherapy has emerged as promising treatment in sarcomas, but the high variability in
terms of histology, clinical behavior and response to treatments determines a particular …

Introduction Sarcomas are classified into two types, bone sarcoma and soft tissue sarcoma
(STS), which account for approximately 1% of adult solid malignancies and 20% of pediatric …

Background Soft tissue sarcoma (STS) is comprised of approximately 80 subtypes, with an
incidence of 4-5 per 100,000 annually in Europe. The National Comprehensive Cancer …

Simple Summary Myxofibrosarcoma (MFS) is one of the most common malignant soft tissue
sarcomas. MFS occurs mostly in the extremities of patients after the fifth decade of life as a …

Simple Summary A total of 217 Japanese patients who underwent surgical resection for
extremity STS were included. The Sarculator-predicted 10-year probability of overall survival …

Primary undifferentiated high-grade pleomorphic sarcoma (UPS) in the mediastinum is
exceptionally rare. This paper reports a unique case of anterior mediastinal UPS in an 84 …

Primary myxofibrosarcoma of the heart, a rare cardiac malignancy, was diagnosed in a
middle-aged female patient exhibiting progressive dyspnea following transthoracic …

Background: Determining the infiltration of carcinomas is essential for the proper follow-up
and treatment of cancer patients. However, it continues to be a diagnostic challenge for …