Dilated cardiomyopathy: genetic determinants and mechanisms
EM McNally, L Mestroni - Circulation research, 2017 - Am Heart Assoc
Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …
Echocardiographic Deformation Imaging for Early Detection of Genetic Cardiomyopathies: JACC Review Topic of the Week
K Taha, FP Kirkels, AJ Teske, FW Asselbergs… - Journal of the American …, 2022 - jacc.org
Clinical screening of the relatives of patients with genetic cardiomyopathies is challenging,
as they often lack detectable cardiac abnormalities at presentation. Life-threatening adverse …
as they often lack detectable cardiac abnormalities at presentation. Life-threatening adverse …
Value of speckle tracking–based deformation analysis in screening relatives of patients with asymptomatic dilated cardiomyopathy
JAJ Verdonschot, JJ Merken… - Cardiovascular …, 2020 - jacc.org
Objectives This study sought to investigate the prevalence of systolic dysfunction using
global longitudinal strain (GLS) and its prognostic value in relatives of dilated …
global longitudinal strain (GLS) and its prognostic value in relatives of dilated …
Contemporary and Future Approaches to Precision Medicine in Inherited Cardiomyopathies: JACC Focus Seminar 3/5
Inherited cardiomyopathies are commonly occurring myocardial disorders that are
associated with substantial morbidity and mortality. Clinical management strategies have …
associated with substantial morbidity and mortality. Clinical management strategies have …
From hypertrophy to heart failure: what is new in genetic cardiomyopathies
N Reza, K Musunuru, AT Owens - Current heart failure reports, 2019 - Springer
Purpose The purpose of this review is to provide an update on the recent advances in the
research and clinical care of patients with the major phenotypes of inherited …
research and clinical care of patients with the major phenotypes of inherited …
[HTML][HTML] Determining the thresholds for abnormal left ventricular strains in healthy subjects by echocardiography: a meta-analysis
Background Left ventricular global longitudinal strain (LVGLS), circumferential strain
(LVGCS) and radial strain (LVGRS) are echocardiographic parameters with wide clinical …
(LVGCS) and radial strain (LVGRS) are echocardiographic parameters with wide clinical …
[HTML][HTML] Differences in Cardiac Mechanics among Genetically At-Risk First-Degree Relatives: The DCM Precision Medicine Study
JE Wilcox, L Beussink-Nelson, J Cao, R Kumar… - medRxiv, 2023 - ncbi.nlm.nih.gov
Aims: Among genetically at-risk first-degree relatives (FDRs) of probands with dilated
cardiomyopathy (DCM), the ability to detect changes in left ventricular (LV) mechanics with …
cardiomyopathy (DCM), the ability to detect changes in left ventricular (LV) mechanics with …
Miocardiopatía dilatada familiar: genética, características clínicas y respuesta al tratamiento en función del genotipo
M Navarro Peñalver - 2020 - portalinvestigacion.um.es
La miocardiopatía dilatada idiopática (MCD) es una enfermedad primaria del músculo
cardiaco caracterizada por dilatación y disfunción sistólica del ventrículo izquierdo, en …
cardiaco caracterizada por dilatación y disfunción sistólica del ventrículo izquierdo, en …