Pulsed electromagnetic therapy in cancer treatment: Progress and outlook

W Xu, X Xie, H Wu, X Wang, J Cai, Z Xu, SE - View, 2022 - Wiley Online Library
Cancer is one of the major diseases that endanger human health. Current treatment options
have low patient tolerance, poor prognosis, and strong side effects. Pulsed electromagnetic …

Palmitic acid dysregulates the Hippo–YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS …

L Yuan, Y Mao, W Luo, W Wu, H Xu, XL Wang… - Journal of Biological …, 2017 - ASBMB
Impaired angiogenesis and wound healing carry significant morbidity and mortality in
diabetic patients. Metabolic stress from hyperglycemia and elevated free fatty acids have …

Targeted therapeutics delivery by exploiting biophysical properties of senescent cells

J Low, B Chan, A Tay - Advanced Functional Materials, 2022 - Wiley Online Library
Cellular senescence refers to a state of irreversible arrest of cell proliferation in response to
various forms of cellular stress. It is known that the accumulation of senescent cells is a …

Biodegradable copper-iodide clusters modulate mitochondrial function and suppress tumor growth under ultralow-dose X-ray irradiation

X Ma, N Lin, Q Yang, P Liu, H Ding, M Xu, F Ren… - Nature …, 2024 - nature.com
Abstract Both copper (Cu2+/+) and iodine (I−) are essential elements in all living organisms.
Increasing the intracellular concentrations of Cu or I ions may efficiently inhibit tumor growth …

Technical feasibility and safety of image-guided biphasic monopolar pulsed electric field ablation of metastatic and primary malignancies

DH Kim, RD Suh, J Chiang, F Abtin, SJ Genshaft… - Journal of Vascular and …, 2024 - Elsevier
Purpose To assess the technical feasibility and safety of image-guided percutaneous
biphasic monopolar pulsed electric field (PEF) ablation of primary and metastatic tumors …

Nano‐pulse stimulation induces changes in the intracellular organelles in rat liver tumors treated in situ

R Nuccitelli, A McDaniel, R Connolly… - Lasers in Surgery …, 2020 - Wiley Online Library
Background and Objectives Nano‐pulse stimulation (NPS) therapy is the application of
ultrafast pulses of high amplitude electrical energy to tissues to influence cell function …

Exploring the Conformational Changes Induced by Nanosecond Pulsed Electric Fields on the Voltage Sensing Domain of a Ca2+ Channel

AR Ruiz-Fernández, L Campos, F Villanelo… - Membranes, 2021 - mdpi.com
Nanosecond Pulsed Electric Field (nsPEF or Nano Pulsed Stimulation, NPS) is a technology
that delivers a series of pulses of high-voltage electric fields during a short period of time, in …

Nanosecond range electric pulse application as a non-viral gene delivery method: Proof of concept

P Ruzgys, V Novickij, J Novickij, S Šatkauskas - Scientific reports, 2018 - nature.com
Current electrotransfection protocols are well-established for decades and, as a rule, employ
long micro-millisecond range electric field pulses to facilitate DNA transfer while application …

Nanosecond pulsed electric fields modulate the expression of the astaxanthin biosynthesis genes psy, crtR-b and bkt 1 in Haematococcus pluvialis

F Bai, C Gusbeth, W Frey, P Nick - Scientific reports, 2020 - nature.com
Nanosecond pulsed electric fields (nsPEFs) have been extensively studied with respect to
cellular responses. Whether nsPEFs can regulate gene expression and to modulate the …

3-Methyladenine-enhanced susceptibility to sorafenib in hepatocellular carcinoma cells by inhibiting autophagy

F Zhao, G Feng, J Zhu, Z Su, R Guo, J Liu… - Anti-Cancer …, 2021 - journals.lww.com
As an effective targeted therapy for advanced hepatocellular carcinoma (HCC), sorafenib
resistance has been frequently reported in recent years, with the activation of autophagy by …