Allenes are a class of unique compounds with two π-orbitals perpendicular to each other.
The first synthesis can be traced back to 1887. 1 They also exist in many natural products …

Many biologically active molecules incorporate carbon− carbon double bond (s) with well-
defined configurations (E or Z), such as β-carotene, 1 polyene antifungal drugs, 2, 3 …

Since the groundbreaking work by Gilman1 in the 1950s, cuprates have become versatile
tools in organic synthesis, more precisely, in 1, 4-addition reactions to R,-unsaturated …

Although the chemistry of copper has a long history [1a-d], the relatively recent discovery of
N-heterocyclic carbene (NHC) as transition-metal supporting ligands has permitted novel …

There are still some synthetic chemists who hesitate to use metal-mediated or-catalysed
reactions. The Pauson–Khand reaction (PKR) is a powerful transformation that has now …

The Pauson±Khand (P±K) reaction, formally a [21211] cycloaddition involving an alkene, an
alkyne and carbon monoxide moieties to form a cyclopentenone, was first discovered in the …

In the past decade transition metal catalyzed reactions of allenes have become increasingly
important. A new principle common in many of these reactions is the presence of functional …

The easy way to allenes: An operationally simple reaction under mild conditions has led to
the direct formation of trisubstituted allenes (see scheme; Ts= 4‐toluenesulfonyl). An …

The use of organometallic reagents for the synthesis of allenes is highly developed, and
several fundamentally different methods are now well established. These include transition …

The [2+ 2+ 1] cyclization of an alkyne, an alkene and carbon monoxide, ie, the Pauson–
Khand reaction, is one of the most powerful tools for constructing a five-membered ring. In …