Neuroinflammatory astrocyte subtypes in the mouse brain

P Hasel, IVL Rose, JS Sadick, RD Kim… - Nature …, 2021 - nature.com
Astrocytes undergo an inflammatory transition after infections, acute injuries and chronic
neurodegenerative diseases. How this transition is affected by time and sex, its …

Modulation of glial function in health, aging, and neurodegenerative disease

KL Hanslik, KM Marino, TK Ulland - Frontiers in Cellular …, 2021 - frontiersin.org
In the central nervous system (CNS), glial cells, such as microglia and astrocytes, are
normally associated with support roles including contributions to energy metabolism …

Astrocyte subtype-specific approach to Alzheimer's disease treatment

S Sarkar, SC Biswas - Neurochemistry International, 2021 - Elsevier
Astrocytes respond to any pathological condition in the central nervous system (CNS)
including Alzheimer's disease (AD), and this response is called astrocyte reactivity. Astrocyte …

Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease

J Rauch, JF Steffen, B Muntau, J Gisbrecht… - Emerging Microbes & …, 2022 - Taylor & Francis
ABSTRACT Human Borna disease virus 1 (BoDV-1) encephalitis is a severe emerging
disease with a very high case-fatality rate. While the clinical disease, case definitions …

Music compensates for altered gene expression in age-related cognitive disorders

A Gómez-Carballa, L Navarro, J Pardo-Seco, X Bello… - Scientific reports, 2023 - nature.com
Extensive literature has explored the beneficial effects of music in age-related cognitive
disorders (ACD), but limited knowledge exists regarding its impact on gene expression. We …

[HTML][HTML] The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression

GI Corsi, VP Gadekar, H Haukedal, NT Doncheva… - Neurobiology of …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive and irreversible brain disorder, which can occur
either sporadically, due to a complex combination of environmental, genetic, and epigenetic …

[HTML][HTML] Chronic intestinal inflammation suppresses brain activity by inducing neuroinflammation in mice

J Mitchell, SJ Kim, C Howe, S Lee, JY Her… - The American Journal of …, 2022 - Elsevier
Chronic gut inflammation such as inflammatory bowel disease is believed to be associated
with neurodegenerative diseases in humans. However, the direct evidence for and the …

P38K and JNK pathways are induced by amyloid-β in astrocyte: Implication of MAPK pathways in astrogliosis in Alzheimer's disease

P Saha, S Guha, SC Biswas - Molecular and Cellular Neuroscience, 2020 - Elsevier
Astrocyte activation is one of the crucial hallmarks of Alzheimer's disease (AD) along with
amyloid-β (Aβ) plaques, neurofibrillary tangles and neuron death. Glial scar and factors …

Astrocyte HIV-1 tat differentially modulates behavior and brain MMP/TIMP balance during short and prolonged induction in transgenic mice

CR Joshi, S Stacy, N Sumien, A Ghorpade… - Frontiers in …, 2020 - frontiersin.org
Despite effective antiretroviral therapy (ART), mild forms of HIV-associated neurocognitive
disorders (HAND) continue to afflict approximately half of all people living with HIV (PLWH) …

A Review on the Protective Effects of Probiotics against Alzheimer's Disease

V Mishra, D Yadav, KS Solanki, B Koul, M Song - Biology, 2023 - mdpi.com
Simple Summary Alzheimer's disease (AD) is one of the most common neurodegenerative
disorders in older adults. It is characterized by difficulty in writing and speech, weak memory …