Alkaloids and isoprenoids modification by copper (I)-catalyzed Huisgen 1, 3-dipolar cycloaddition (click chemistry): toward new functions and molecular architectures

K Kacprzak, I Skiera, M Piasecka, Z Paryzek - Chemical reviews, 2016 - ACS Publications
Despite enormous progress in the field of the synthetic chemistry involving, for example,
catalytic and combinatorial synthesis of a large libraries of compounds, multicomponent …

Recent advancements in 1, 4-disubstituted 1H-1, 2, 3-triazoles as potential anticancer agents

K Lal, P Yadav - Anti-Cancer Agents in Medicinal Chemistry …, 2018 - ingentaconnect.com
Cancer is a class of formidable disease with high degree of mortality. Despite much
progress in chemotherapy, the problem of drug resistance has led to the search for newer …

Applications of Sharpless asymmetric epoxidation in total synthesis

MM Heravi, TB Lashaki, N Poorahmad - Tetrahedron: Asymmetry, 2015 - Elsevier
This report presents the applications of enantioselective epoxidation of prochiral allylic
alcohols, so called 'Sharpless asymmetric epoxidation', which is frequently referred as …

Naphthol-derived Betti bases as potential SLC6A14 blockers

A Puerta, AR Galán, R Abdilla, K Demanuele… - 2019 - um.edu.mt
Betti bases (aminobenzylnaphthols) have not been studied extensively to explore their
possible pharmacological applications. Our group prepared a small and focused library of …

Copaifera duckei Oleoresin and Its Main Nonvolatile Terpenes: In Vitro Schistosomicidal Properties

CHG Borges, MG Cruz, LJ Carneiro… - Chemistry & …, 2016 - Wiley Online Library
In this article, the in vitro schistosomicidal effects of three Brazilian Copaifera oleoresins (C.
duckei, C. langsdorffii, and C. reticulata) are reported. From these botanical sources, the …

Exploring diterpene metabolism in non‐model species: transcriptome‐enabled discovery and functional characterization of labda‐7, 13E‐dienyl diphosphate …

P Zerbe, SM Rodriguez, S Mafu, A Chiang… - The Plant …, 2015 - Wiley Online Library
Grindelia robusta or gumweed, is a medicinal herb of the sunflower family that forms a
diverse suite of diterpenoid natural products. Its major constituents, grindelic acid and …

[PDF][PDF] Non-pharmacological remedies for post-viral acute cough

G Ciprandi, MA Tosca - Monaldi Archives for Chest Disease, 2022 - monaldi-archives.org
The post-viral acute cough (PAC) is a widespread symptom, mainly in childhood and
adolescence, and is usually associated with an acute upper respiratory infection, namely the …

Ugi adducts of isatin as promising antiproliferative agents with druglike properties

P Brandão, A Puerta, JM Padrón… - Asian Journal of …, 2021 - Wiley Online Library
Multicomponent reactions (MCRs) are a valuable tool for the sustainable synthesis of new
molecules in a fast, effective and eco‐friendly manner, leading to the generation of …

[图书][B] Foods and dietary supplements in the prevention and treatment of disease in older adults

RR Watson - 2015 - books.google.com
Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults
focuses on the ways in which food and dietary supplements affect the major health problems …

In Vitro, In Vivo, and In Silico Studies of Cumanin Diacetate as a Potential Drug against Trypanosoma cruzi Infection

A Sanchez Alberti, MF Beer, N Cerny, AE Bivona… - ACS …, 2021 - ACS Publications
The sesquiterpene lactones cumanin, helenalin, and hymenin and their semisynthetic
derivatives were evaluated against Trypanosoma cruzi epimastigotes. The cytotoxicity of the …