Spontaneous neuronal activity in developing neocortical networks: from single cells to large-scale interactions

HJ Luhmann, A Sinning, JW Yang… - Frontiers in neural …, 2016 - frontiersin.org
Neuronal activity has been shown to be essential for the proper formation of neuronal
circuits, affecting developmental processes like neurogenesis, migration, programmed cell …

Electrophysiological correlates of sleep homeostasis in freely behaving rats

VV Vyazovskiy, C Cirelli, G Tononi - Progress in brain research, 2011 - Elsevier
The electrical activity of the brain does not only reflect the current level of arousal, ongoing
behavior, or involvement in a specific task but is also influenced by what kind of activity, and …

GABA depolarizes immature neurons and inhibits network activity in the neonatal neocortex in vivo

K Kirmse, M Kummer, Y Kovalchuk, OW Witte… - Nature …, 2015 - nature.com
A large body of evidence from in vitro studies suggests that GABA is depolarizing during
early postnatal development. However, the mode of GABA action in the intact developing …

Adaptation of spontaneous activity in the developing visual cortex

ME Wosniack, JH Kirchner, LY Chao, N Zabouri… - Elife, 2021 - elifesciences.org
Spontaneous activity drives the establishment of appropriate connectivity in different circuits
during brain development. In the mouse primary visual cortex, two distinct patterns of …

A microfluidic microelectrode array for simultaneous electrophysiology, chemical stimulation, and imaging of brain slices

A Scott, K Weir, C Easton, W Huynh, WJ Moody… - Lab on a Chip, 2013 - pubs.rsc.org
In order to understand information processing in neural circuits, it is necessary to detect both
electrical and chemical signaling with high spatial and temporal resolution. Although the …

Intrinsic neuronal properties switch the mode of information transmission in networks

J Gjorgjieva, RA Mease, WJ Moody… - PLoS computational …, 2014 - journals.plos.org
Diverse ion channels and their dynamics endow single neurons with complex biophysical
properties. These properties determine the heterogeneity of cell types that make up the …

Layer III neurons control synchronized waves in the immature cerebral cortex

S Namiki, H Norimoto, C Kobayashi… - Journal of …, 2013 - Soc Neuroscience
Correlated spiking activity prevails in immature cortical networks and is believed to
contribute to neuronal circuit maturation; however, its spatiotemporal organization is not fully …

Emergence of adaptive computation by single neurons in the developing cortex

RA Mease, M Famulare, J Gjorgjieva… - Journal of …, 2013 - Soc Neuroscience
Adaptation is a fundamental computational motif in neural processing. To maintain stable
perception in the face of rapidly shifting input, neural systems must extract relevant …

Spatial embryonic origin delineates GABAergic hub neurons driving network dynamics in the developing entorhinal cortex

L Mòdol, VH Sousa, A Malvache, T Tressard… - Cerebral …, 2017 - academic.oup.com
Coordinated neuronal activity is essential for the development of cortical circuits. GABAergic
hub neurons that function in orchestrating early neuronal activity through a widespread net …

SamuROI, a Python-based software tool for visualization and analysis of dynamic time series imaging at multiple spatial scales

M Rueckl, SC Lenzi, L Moreno-Velasquez… - Frontiers in …, 2017 - frontiersin.org
The measurement of activity in vivo and in vitro has shifted from electrical to optical methods.
While the indicators for imaging activity have improved significantly over the last decade …