[HTML][HTML] Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia

R Marín, DI Chiarello, C Abad, D Rojas… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …

Placental Senescence and the Two‐Stage Model of Preeclampsia

M Sugulle, BS Fiskå, DP Jacobsen… - American Journal of …, 2024 - Wiley Online Library
In this review, we summarize how an increasingly stressed and aging placenta contributes
to the maternal clinical signs of preeclampsia, a potentially lethal pregnancy complication …

SIRT1 regulates trophoblast senescence in premature placental aging in preeclampsia

YJ Wang, Y Zhang, Y Wu, Y He, J Xiang, J Huang… - Placenta, 2022 - Elsevier
Introduction Premature placental aging is implicated in a number of complications of
pregnancy including preeclampsia. A placenta knockout mouse model has shown a …

Resveratrol induces SIRT1-Dependent autophagy to prevent H2O2-Induced oxidative stress and apoptosis in HTR8/SVneo cells

P Wang, C Huang, J Gao, Y Shi, H Li, H Yan, S Yan… - Placenta, 2020 - Elsevier
Introduction Pre-eclampsia (PE) is a serious complication of pregnancy, and the likely
pathogenic basis of early onset PE are placental dysfunction and increased oxidative stress …

SIRT3 deficiency affects the migration, invasion, tube formation and necroptosis of trophoblast and is implicated in the pathogenesis of preeclampsia

H Yu, Y Zhang, M Liu, L Liao, X Wei, R Zhou - Placenta, 2022 - Elsevier
Abstract Introduction Sirtuin 3 (SIRT3) plays a key role in many diseases by regulating cell
necroptosis and biological behavior. However, the exact role of SIRT3 in preeclampsia …

Analysis of SIRT1 Expression in Plasma and in an In Vitro Model of Preeclampsia

S Viana-Mattioli, P Nunes, R Cavalli… - … Medicine and Cellular …, 2020 - Wiley Online Library
Preeclampsia (PE) is a pregnancy‐specific disorder that affects 3–8% expecting mothers
worldwide being one of the main causes of maternal and fetal morbidity and mortality. The …

Can adipokine visfatin be a novel marker of pregnancy‐related disorders in women with obesity?

A Wnuk, A Stangret, M Wątroba, AE Płatek… - Obesity …, 2020 - Wiley Online Library
Overweight and obesity have become a dangerous disease requiring multiple interventions,
treatment and preventions. In women of reproductive age, obesity is one of the most …

[HTML][HTML] SIRT1-dependent effects of resveratrol and grape juice in an in vitro model of preeclampsia

S Viana-Mattioli, N Cinegaglia… - Biomedicine & …, 2020 - Elsevier
Preeclampsia (PE) is a multifactorial hypertensive disorder of pregnancy that is partly
responsible for both maternal and fetal morbidity and mortality levels worldwide. It has been …

Mitochondrial transformations in the aging human placenta

LA Bartho, JJ Fisher, JSM Cuffe… - American Journal of …, 2020 - journals.physiology.org
Mitochondria play a key role in homeostasis and are central to one of the leading
hypotheses of aging, the free radical theory. Mitochondria function as a reticulated network …

Maternal psychological stress during pregnancy and newborn telomere length: a systematic review and meta-analysis

R Moshfeghinia, A Torabi, S Mostafavi, S Rahbar… - BMC psychiatry, 2023 - Springer
Introduction Telomeres protect the ends of chromosomes, and shorter leukocyte telomeres
are associated with major group diseases. Maternal psychological stress may be related to …