Therapeutic strategies to overcome cisplatin resistance in ovarian cancer

M Song, M Cui, K Liu - European journal of medicinal chemistry, 2022 - Elsevier
Ovarian cancer (OC) is one of the most common gynecologic tumors worldwide and one
with the highest mortality. Cisplatin (DDP) is the first platinum-based complex approved by …

Promising heterometallic compounds as anticancer agents: Recent studies in vivo

JE López-Hernández, M Contel - Current opinion in chemical biology, 2023 - Elsevier
Over the past decade, interest on multitarget anticancer drugs-including heterometallic
compounds-has increased considerably. Heterometallic species display improved efficacy …

Easily available, amphiphilic diiron cyclopentadienyl complexes exhibit in vitro anticancer activity in 2D and 3D human cancer cells through redox modulation …

L Biancalana, M De Franco… - … A European Journal, 2021 - Wiley Online Library
A straightforward two‐step procedure via single CO removal allows the conversion of
commercial [Fe2Cp2 (CO) 4] into a range of amphiphilic and robust ionic complexes based …

Homo and Heteromultimetallic Complexes Containing a Group 8 Transition Metal and μ-diphosphine Bridging Ligands Involved in Anticancer Research: A Review

B Roufosse, C Serbu, C Marschner, S Prince… - European Journal of …, 2024 - Elsevier
Herein, we present a comprehensive review focusing on synthetic strategies, detailed
structural analysis, and anticancer activity investigations of complexes following the general …

Design of hydroxyl-and thioether-functionalized iron-platinum dimetallacyclopentenone complexes. Crystal and electronic structures, Hirshfeld and docking analyses …

AS Mohamed, I Jourdain, M Knorr, A Elmi… - Journal of Molecular …, 2022 - Elsevier
A series of metal-metal bonded iron-platinum heterobimetallic complexes has been
prepared by carbon-carbon coupling of [(OC) 3 Fe (µ-C= O)(µ-dppm) Pt (PPh 3)](1)(dppm …

Ionic mononuclear [Fe] and heterodinuclear [Fe, Ru] bis (diphenylphosphino) alkane complexes: Synthesis, spectroscopy, DFT structures, cytotoxicity, and …

M Odachowski, R Neven, G Perversi, D Romano… - Journal of Inorganic …, 2023 - Elsevier
Abstract Iron (II) and Ru (II) half-sandwich compounds encompass some promising pre-
clinical anticancer agents whose efficacy may be tuned by structural modification of the …

A mononuclear Co (II) complex: Crystal structure, thermal behavior, optical properties and biological activities

S Dgachi, F Rahmouni, A Soran, M Saoudi… - Journal of Molecular …, 2021 - Elsevier
A new mononuclear cobalt hybrid material (C 6 H 9 N 2) 2 [CoCl 4] was prepared using slow
evaporation technique at room temperature. The X-ray diffraction analysis revealed that the …

Tethering Carbohydrates to the Vinyliminium Ligand of Antiproliferative Organometallic Diiron Complexes

S Schoch, D Iacopini, M Dalla Pozza, S Di Pietro… - …, 2022 - ACS Publications
Four propargyl O-glycosides derivatized with mannose, glucose, and fructose moieties were
synthesized and then incorporated within a diiron structure as part of a vinyliminium ligand …

Piano stool iron complexes with isocyanide ligands

G Bresciani, S Volante, L Biancalana, S Zacchini… - Journal of …, 2023 - Elsevier
Abstract Complexes [FeCpI (CO)(CNR)][2a-f; R= 2, 6-C 6 H 3 Me 2= Xyl, 4-C 6 H 4 OMe, CH
2 Ph, CH 2 P (O)(OEt) 2, CH 2 SO 2 (4-C 6 H 4 Me), Me; Cp= η 5-C 5 H 5] and [FeCpI (CNR) …

A critical analysis of the potential of iron heterobimetallic complexes in anticancer research

B Tűz, I Correia, PN Martinho - Journal of Inorganic Biochemistry, 2024 - Elsevier
Due to their diverse chemical properties and high ability to interact with biological molecules
and cellular processes, transition metal-based compounds have emerged as promising …