Epigenetic changes associated with histone modifications play an important role in the
emergence and maintenance of the phenotype of various cancer types. In contrast to direct …

Skeletal muscular atrophy is a complex disease involving a large number of gene
expression regulatory networks and various biological processes. Despite extensive …

Cancer cachexia is a lethal metabolic syndrome featuring muscle wasting with preferential
loss of fast-twitching muscle mass through an undefined mechanism. Here, we show that …

Cancer-associated cachexia, characterized by muscle wasting, is a lethal metabolic
syndrome without defined etiology or established treatment. We previously found that p300 …

Background Ghrelin is a potential therapy for cachexia due to its orexigenic properties and
anabolic effects on muscle and fat. However, its clinical use is limited by the short half‐life of …

The clinical correlation between adiponectin (APN) signal and hypertrophic scar (HS)
remains unclear. Here, we found significantly reduced expression of APN receptors …

Cancer-associated cachexia (cancer cachexia) is a major contributor to the modality and
mortality of a wide variety of solid tumors. It is estimated that cachexia inflicts approximately …

Skeletal muscle atrophy, characterized by diminished muscle strength and mass, arises from
various causes, including malnutrition, aging, nerve damage, and disease-related …

The emergence of targeted therapies and immunotherapies has improved the overall
survival of patients with nonsmall cell lung cancer (NSCLC), but the 5-year survival rate …

Unintentional weight loss, a first clinical sign of muscle wasting, is a major threat to cancer
survival without a defined etiology. We previously identified in mice that p38β MAPK …