Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

Aspirin (acetylsalicylic acid) has become one of the most commonly used drugs, given its
role as an analgesic, antipyretic and agent for cardiovascular prophylaxis. Several decades …

PGE 2, an essential homeostatic factor, is also a key mediator of immunopathology in
chronic infections and cancer. The impact of PGE 2 reflects the balance between its …

Abstract Prostaglandin E 2 (PGE 2) is a bioactive lipid that elicits a wide range of biological
effects associated with inflammation and cancer. PGE 2 exerts diverse effects on cell …

Eicosanoids, including prostaglandins and leukotrienes, are biologically active lipids that
have been implicated in various pathological processes, such as inflammation and cancer …

Colorectal cancer has been strongly associated with a Western lifestyle. In the past several
decades, much has been learned about the dietary, lifestyle, and medication risk factors for …

Colorectal cancer (CRC) is a heterogeneous disease, including at least three major forms:
hereditary, sporadic and colitis-associated CRC. A large body of evidence indicates that …

For decades, lipid droplets have been considered as the main cellular organelles involved
in the fat storage, because of their lipid composition. However, in recent years, some new …

INTRODUCTION Agents that promote tissue regeneration could be beneficial in a variety of
clinical settings, such as stimulating recovery of the hematopoietic system after bone marrow …

Background Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) with anti-
inflammatory, analgestic, and antipyretic properties. It is approved for the treatment of …