Significant controversy has emerged over the last decade concerning the effects of vitamin D
on skeletal and nonskeletal tissues. The demonstration that the vitamin D receptor is …

Vitamin D production in the skin under the influence of sunlight (UVB) is maximized at levels
of sunlight exposure that do not burn the skin. Further metabolism of vitamin D to its major …

The interest in vitamin D continues unabated with thousands of publications contributing to a
vast and growing literature each year. It is widely recognized that the vitamin D receptor …

The sensitivity of fluorescence polarization (FP) and fluorescence anisotropy (FA) to
molecular weight changes has enabled the interrogation of diverse biological mechanisms …

The keratinocytes of the skin are unique in being not only the primary source of vitamin D for
the body, but in possessing the enzymatic machinery to metabolize vitamin D to its active …

The keratinocytes of the skin are unique in being not only the primary source of vitamin D for
the body, but in possessing both the enzymatic machinery to metabolize the vitamin D …

The activities of 1α, 25-dihydroxyvitamin D3, 1, 25D3, are mediated via its binding to the
vitamin D receptor (VDR), a ligand-dependent transcription factor that belongs to the nuclear …

The metabolite of vitamin D, 1α, 25-dihydroxyvitamin D3 (also known as calcitriol), is a
biologically active molecule required to maintain the physiological functions of several target …

Women in North America have a one in eight lifetime risk of developing breast cancer (BC),
and a significant proportion of these individuals will develop recurrent BC and will eventually …

Recurrent pregnancy loss (RPL) is a common complication in obstetrics, affecting about 5%
of women of childbearing age. An increase in the number of abortions results in escalation …