Reactive astrocyte nomenclature, definitions, and future directions

C Escartin, E Galea, A Lakatos, JP O'Callaghan… - Nature …, 2021 - nature.com
Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling …

Blood‐based biomarkers for Alzheimer's disease

A Leuzy, N Mattsson‐Carlgren, S Palmqvist… - EMBO molecular …, 2022 - embopress.org
Neurodegenerative disorders such as Alzheimer's disease (AD) represent a mounting public
health challenge. As these diseases are difficult to diagnose clinically, biomarkers of …

[HTML][HTML] Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

MJ Workman, RG Lim, J Wu, A Frank, L Ornelas… - Neuron, 2023 - cell.com
Using induced pluripotent stem cells (iPSCs) to understand the mechanisms of neurological
disease holds great promise; however, there is a lack of well-curated lines from a large array …

Cytokine release syndrome‐associated encephalopathy in patients with COVID‐19

P Perrin, N Collongues, S Baloglu… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Neurological manifestations in coronavirus disease (COVID)‐
2019 may adversely affect clinical outcomes. Severe COVID‐19 and uremia are risk factors …

S100B, actor and biomarker of mild traumatic brain injury

C Oris, S Kahouadji, J Durif, D Bouvier… - International Journal of …, 2023 - mdpi.com
Mild traumatic brain injury (mTBI) accounts for approximately 80% of all TBI cases and is a
growing source of morbidity and mortality worldwide. To improve the management of …

MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles

T Kammann, C Cai, T Sekine, E Mouchtaridi… - Science …, 2024 - science.org
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that recognize
microbial riboflavin pathway metabolites presented by evolutionarily conserved MR1 …

Serum S100B protein as a marker of severity in Covid-19 patients

A Aceti, LM Margarucci, E Scaramucci, M Orsini… - Scientific reports, 2020 - nature.com
SARS-CoV-2 infection shows a wide-ranging clinical severity, requiring prognostic markers.
We focused on S100B, a calcium-binding protein present in biological fluids, being a …

Pesticides at brain borders: Impact on the blood-brain barrier, neuroinflammation, and neurological risk trajectories

N Cresto, I Forner-Piquer, A Baig, M Chatterjee… - Chemosphere, 2023 - Elsevier
Pesticides are omnipresent, and they pose significant environmental and health risks.
Translational studies indicate that acute exposure to high pesticide levels is detrimental, and …

[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Targeting S100B protein as a surrogate biomarker and its role in various neurological disorders

U Langeh, S Singh - Current neuropharmacology, 2021 - ingentaconnect.com
Neurological disorders (ND) are the central nervous system (CNS) related complications
originated by enhanced oxidative stress, mitochondrial failure and overexpression of …