Membrane fusion studied by colloidal probes

H Witt, F Savić, S Verbeek, J Dietz, G Tarantola… - European Biophysics …, 2021 - Springer
Membrane-coated colloidal probes combine the benefits of solid-supported membranes with
a more complex three-dimensional geometry. This combination makes them a powerful …

The trans-SNARE-regulating function of Munc18-1 is essential to synaptic exocytosis

C Shen, SS Rathore, H Yu, DR Gulbranson… - Nature …, 2015 - nature.com
The fusion of neurotransmitter-filled synaptic vesicles with the plasma membrane requires
two classes of molecules—SNAP receptor (SNARE) and Sec1/Munc18 (SM) protein …

[PDF][PDF] Reconciling the regulatory role of Munc18 proteins in SNARE-complex assembly

A Rehman, JK Archbold, SH Hu, SJ Norwood… - IUCrJ, 2014 - journals.iucr.org
Membrane fusion is essential for human health, playing a vital role in processes as diverse
as neurotransmission and blood glucose control. Two protein families are key:(1) the …

Bioengineered yeast-derived vacuoles with enhanced tissue-penetrating ability for targeted cancer therapy

V Gujrati, M Lee, YJ Ko, S Lee, D Kim… - Proceedings of the …, 2016 - National Acad Sciences
Despite the appreciable success of synthetic nanomaterials for targeted cancer therapy in
preclinical studies, technical challenges involving their large-scale, cost-effective production …

SNAREs support atlastin-mediated homotypic ER fusion in Saccharomyces cerevisiae

M Lee, YJ Ko, Y Moon, M Han, HW Kim, SH Lee… - Journal of Cell …, 2015 - rupress.org
Dynamin-like GTPases of the atlastin family are thought to mediate homotypic endoplasmic
reticulum (ER) membrane fusion; however, the underlying mechanism remains largely …

[HTML][HTML] Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal …

Q Bourgeois-Jaarsma, PM Hernandez… - Molecular and Cellular …, 2021 - Elsevier
Presynaptic neurotransmitter release is strictly regulated by SNARE proteins, Ca 2+ and a
number of Ca 2+ sensors including synaptotagmins (Syts) and Double C 2 domain proteins …

A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion

RP Sparks, AS Arango, ML Starr, ZL Aboff… - Journal of Biological …, 2019 - ASBMB
The homeostasis of most organelles requires membrane fusion mediated by soluble N-
ethylmaleimide–sensitive factor (NSF) attachment protein receptors (SNAREs). SNAREs …

Buforin-1 blocks neuronal SNARE-mediated membrane fusion by inhibiting SNARE complex assembly

JG Lee, YJ Ko, JH Choi, MJ Jo, Y Jun, JI Kim - Biochemical and biophysical …, 2019 - Elsevier
Assembly of neuronal SNARE protein complexes is essential for fusion of synaptic vesicles
with the presynaptic plasma membrane, which releases neurotransmitters into the synaptic …

Acclimation of Chlamydomonas reinhardtii to Nitric Oxide Stress Related to Respiratory Burst Oxidase-Like 2

EYH Kuo, TM Lee - bioRxiv, 2021 - biorxiv.org
The acclimation mechanism of Chlamydomonas reinhardtii to nitric oxide (NO) was studied
by exposure to S-nitroso-N-acetylpenicillamine (SNAP), a NO donor. Treatment with 0.1 or …

[PDF][PDF] VU Research Portal

Q Bourgeois-Jaarsma - research.vu.nl
As introduced in chapter 1, release of SVs can be evoked by action potentials or they can be
released in their absence. Cytosolic Ca2+ plays a role in both forms of release. The Double …