Ovarian cancer is the third most common gynecologic malignancy worldwide but accounts for the highest mortality rate among these cancers. A stepwise approach to assessment …
The development of guidelines recommendations is one of the core activities of the European Society for Medical Oncology (ESMO) and European Society of Gynaecologial …
Epithelial ovarian cancer generally presents at an advanced stage and is the most common cause of gynaecological cancer death. Treatment requires expert multidisciplinary care …
A Chandra, C Pius, M Nabeel, M Nair… - Cancer …, 2019 - Wiley Online Library
Of all the gynecologic tumors, ovarian cancer (OC) is known to be the deadliest. Advanced‐ stages of OC are linked with high morbidity and low survival rates despite the immense …
Ovarian cancer is not a single disease and can be subdivided into at least five different histological subtypes that have different identifiable risk factors, cells of origin, molecular …
The folate receptor (FR) is a recognised biomarker for tumour cells due to its overexpression on a large number of tumours. Consequently, the FR has been exploited by many diagnostic …
RL Coleman, MF Brady, TJ Herzog, P Sabbatini… - The Lancet …, 2017 - thelancet.com
Background Platinum-based chemotherapy doublets are a standard of care for women with ovarian cancer recurring 6 months after completion of initial therapy. In this study, we aimed …
A González-Martín, P Harter, A Leary… - Annals of …, 2023 - annalsofoncology.org
Epithelial ovarian cancer (EOC) represents a heterogeneous spectrum of disease entities at a clinical, pathological and molecular level. Ovarian cancer is the second most lethal …
Approximately 50% of epithelial ovarian cancers (EOC) exhibit defective DNA repair via homologous recombination (HR) due to genetic and epigenetic alterations of HR pathway …