Making sense of rapidly evolving evidence on genetic associations is crucial to making
genuine advances in human genomics and the eventual integration of this information in the …

Although genotyping errors affect most data and can markedly influence the biological
conclusions of a study, they are too often neglected. Errors have various causes, but their …

Abstract Testing for Hardy–Weinberg proportions (HWP) is routine in almost all genetic
studies of natural populations, but many researchers do not demonstrate a full …

Genetic methods are routinely used to estimate contemporary effective population size (Ne)
in natural populations, but the vast majority of applications have used only the temporal (two …

Genotyping errors occur when the genotype determined after molecular analysis does not
correspond to the real genotype of the individual under consideration. Virtually every genetic …

Abstract Analysis of linkage disequilibrium (̂ r^ 2= mean squared correlation of allele
frequencies at different gene loci) provides a means of estimating effective population size …

Identifying genomic regions that have been targets of natural selection remains one of the
most important and challenging areas of research in genetics. To this end, we report an …

Association mapping is rapidly becoming the main method for dissecting the genetic
architecture of complex traits in plants. Currently most association mapping studies in plants …

The identification and characterization of genes that influence the risk of common, complex
multifactorial diseases, primarily through interactions with other genes and other …

Genotyping data sets may contain errors that, in some instances, lead to false conclusions.
Deviation from Hardy–Weinberg equilibrium (HWE) in random samples may be indicative of …