The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors

ID Neumann, R Landgraf - Trends in neurosciences, 2012 - cell.com
Oxytocin and vasopressin are regulators of anxiety, stress-coping, and sociality. They are
released within hypothalamic and limbic areas from dendrites, axons, and perikarya …

[HTML][HTML] Mechanisms underlying microbial-mediated changes in social behavior in mouse models of autism spectrum disorder

M Sgritta, SW Dooling, SA Buffington, EN Momin… - Neuron, 2019 - cell.com
Currently, there are no medications that effectively treat the core symptoms of Autism
Spectrum Disorder (ASD). We recently found that the bacterial species Lactobacillus (L.) …

A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments

T Qian, H Wang, P Wang, L Geng, L Mei… - Nature …, 2023 - nature.com
Oxytocin (OT), a peptide hormone and neuromodulator, is involved in diverse physiological
and pathophysiological processes in the central nervous system and the periphery …

Dissecting the contribution of host genetics and the microbiome in complex behaviors

SA Buffington, SW Dooling, M Sgritta, C Noecker… - Cell, 2021 - cell.com
The core symptoms of many neurological disorders have traditionally been thought to be
caused by genetic variants affecting brain development and function. However, the gut …

[HTML][HTML] Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring

SA Buffington, GV Di Prisco, TA Auchtung, NJ Ajami… - Cell, 2016 - cell.com
Maternal obesity during pregnancy has been associated with increased risk of
neurodevelopmental disorders, including autism spectrum disorder (ASD), in offspring …

Oxytocin, motivation and the role of dopamine

TM Love - Pharmacology Biochemistry and Behavior, 2014 - Elsevier
The hypothalamic neuropeptide oxytocin has drawn the attention of scientists for more than
a century. The understanding of the function of oxytocin has expanded dramatically over the …

Oxytocin: the great facilitator of life

HJ Lee, AH Macbeth, JH Pagani, WS Young 3rd - Progress in neurobiology, 2009 - Elsevier
Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and parturition.
Since 1906 when its uterine-contracting properties were described until 50 years later when …

Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice

M Yoshida, Y Takayanagi, K Inoue… - Journal of …, 2009 - Soc Neuroscience
The oxytocin receptor has been implicated in the regulation of reproductive physiology as
well as social and emotional behaviors. The neurochemical mechanisms by which oxytocin …

Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits

DA Baribeau, E Anagnostou - Frontiers in neuroscience, 2015 - frontiersin.org
Oxytocin and vasopressin are pituitary neuropeptides that have been shown to affect social
processes in mammals. There is growing interest in these molecules and their receptors as …