Background Spatial and temporal changes in the dengue incidence are associated with
multiple factors, such as climate, immunity among a population against dengue viruses …

Abstract Introduction Dengue virus (DENV) NS1 is a non-structural secretory protein
associated with severe disease and known to cause vascular leak leading to dengue …

ABSTRACT Objective Systematic Literature review conducted to observe changes in the
epidemiological pattern of dengue disease in Sri Lanka during the period of 2000-2020 …

The largest ever Sri Lankan dengue outbreak of 2017 provides an opportunity for
investigating the relative contributions of climatological, epidemiological and sociological …

Introduction Although the role of dengue virus (DENV)‐specific T cells in the pathogenesis of
acute dengue infection is emerging, the functionality of virus‐specific T cells associated with …

To further understand the role of NS1‐specific antibodies (Abs) in disease pathogenesis, we
compared neutralizing antibody levels (Nabs), NS1‐Ab levels, IgG antibody subclass …

The incidence of dengue virus disease has increased globally across the past half-century,
with highest number of cases ever reported in 2019 and again in 2023. We analyzed …

Synthetic peptides have recently become common as antigens for antibody production.
Peptides are short chains of amino acids that can be used to elicit an immune response. The …

Dengue is among the deadliest insect-borne diseases circulating in Sri Lanka. Most of the
infections that are diagnosed early are manageable. However, delays in diagnosis may …

Dengue is a major viral disease affecting the tropics. Although previous research has
focused on the relationship between the infecting dengue virus (DENV) serotypes and …