Reactive oxygen species, such as superoxide and hydrogen peroxide, are generated in all
cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can …

Wound healing requires a fine balance between the positive and deleterious effects of
reactive oxygen species (ROS); a group of extremely potent molecules, rate limiting in …

The activation of nuclear factor-kappaB (NFΚB), a proinflammatory transcription factor, is a
commonly observed phenomenon in breast cancer. It facilitates the development of a …

The present study evaluated the effect of dietary sodium butyrate (SB) supplementation on
the growth and immune function in the proximal intestine (PI), middle intestine (MI) and distal …

The phagocyte NAPDH–oxidase complex consists of several phagocyte oxidase (phox)
proteins, generating reactive oxygen species (ROS) upon activation. ROS are involved in …

Abstract Hydrogen peroxide (H2O2) has been implicated in the regulation of the
transcription factor NF-κB, a key regulator of the inflammatory process and adaptive …

The pathophysiological functions of proline-glutamic acid (PE)/proline-proline-glutamic acid
(PPE) family of proteins of Mycobacterium tuberculosis are not well understood. In this study …

c-Rel is a member of the nuclear factor κB (NF-κB) transcription factor family. Unlike other NF-
κB proteins that are expressed in a variety of cell types, high levels of c-Rel expression are …

Oxidative stress during sepsis pathogenesis remains the most-important factor creating
imbalance and dysregulation in immune-cell function, usually observed following initial …

Background Abnormal immune responses are believed to be highly relevant in the
pathogenesis of chronic obstructive pulmonary disease (COPD). Dendritic cells provide a …