Identification and prioritization of environmental organic pollutants: from an analytical and toxicological perspective
Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …
and adverse health outcomes, which have been received substantial and increasing …
Assessing the ecological risks of per‐and polyfluoroalkyl substances: Current state‐of‐the science and a proposed path forward
Per‐and poly‐fluoroalkyl substances (PFAS) encompass a large, heterogenous group of
chemicals of potential concern to human health and the environment. Based on information …
chemicals of potential concern to human health and the environment. Based on information …
[HTML][HTML] (Eco) toxicological tests for assessing impacts of chemical stress to aquatic ecosystems: facts, challenges, and future
LM Schuijt, FJ Peng, SJP van den Berg… - Science of the total …, 2021 - Elsevier
Monitoring of chemicals in the aquatic environment by chemical analysis alone cannot
completely assess and predict the effects of chemicals on aquatic species and ecosystems …
completely assess and predict the effects of chemicals on aquatic species and ecosystems …
Species sensitivity to toxic substances: Evolution, ecology and applications
Because it is only possible to test chemicals for effects on a restricted range of species and
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …
Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption
AC Haigis, L Vergauwen, CA LaLone… - Toxicological …, 2023 - academic.oup.com
Thyroid hormone system disrupting compounds are considered potential threats for human
and environmental health. Multiple adverse outcome pathways (AOPs) for thyroid hormone …
and environmental health. Multiple adverse outcome pathways (AOPs) for thyroid hormone …
Toward an AOP network-based tiered testing strategy for the assessment of thyroid hormone disruption
D Knapen, E Stinckens, JE Cavallin… - Environmental …, 2020 - ACS Publications
A growing number of environmental pollutants are known to adversely affect the thyroid
hormone system, and major gaps have been identified in the tools available for the …
hormone system, and major gaps have been identified in the tools available for the …
Potential toxicity of complex mixtures in surface waters from a nationwide survey of United States streams: Identifying in vitro bioactivities and causative chemicals
While chemical analysis of contaminant mixtures remains an essential component of
environmental monitoring, bioactivity-based assessments using in vitro systems increasingly …
environmental monitoring, bioactivity-based assessments using in vitro systems increasingly …
High‐throughput screening and environmental risk assessment: State of the science and emerging applications
ABSTRACT In 2007 the United States National Research Council (NRC) published a vision
for toxicity testing in the 21st century that emphasized the use of in vitro high‐throughput …
for toxicity testing in the 21st century that emphasized the use of in vitro high‐throughput …
Three perspectives on the prediction of chemical effects in ecosystems
A Schneeweiss, NPD Juvigny‐Khenafou… - Global Change …, 2023 - Wiley Online Library
The increasing production, use and emission of synthetic chemicals into the environment
represents a major driver of global change. The large number of synthetic chemicals, limited …
represents a major driver of global change. The large number of synthetic chemicals, limited …
AOP report: Thyroperoxidase inhibition leading to altered visual function in fish via altered retinal layer structure
L Gölz, L Baumann, P Pannetier… - Environmental …, 2022 - Wiley Online Library
Thyroid hormones (THs) are involved in the regulation of many important physiological and
developmental processes, including vertebrate eye development. Thyroid hormone system …
developmental processes, including vertebrate eye development. Thyroid hormone system …