Diagnosis of human preimplantation embryo viability

DK Gardner, M Meseguer, C Rubio… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Transfer of more than a single embryo in an IVF cycle comes with the finite
possibility of a multiple gestation. Even a twin pregnancy confers significant risk to both …

Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcomes

P Hernández-Vargas, M Muñoz… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Successful embryo implantation is a complex process that requires the
coordination of a series of events, involving both the embryo and the maternal endometrium …

The use of morphokinetics as a predictor of embryo implantation

M Meseguer, J Herrero, A Tejera… - Human …, 2011 - academic.oup.com
BACKGROUND Time-lapse observation presents an opportunity for optimizing embryo
selection based on morphological grading as well as providing novel kinetic parameters …

Metabolomics as a tool to identify biomarkers to predict and improve outcomes in reproductive medicine: a systematic review

T Bracewell-Milnes, S Saso, H Abdalla… - Human …, 2017 - academic.oup.com
BACKGROUND Infertility is a complex disorder with significant medical, psychological and
financial consequences for patients. With live-birth rates per cycle below 30% and a drive …

OMICS in assisted reproduction: possibilities and pitfalls

E Seli, C Robert, MA Sirard - MHR: Basic science of …, 2010 - academic.oup.com
A key step in assisted reproduction is the assessment of oocyte and embryo developmental
potential in order to determine the embryo (s) most likely to result in pregnancy. Currently …

[HTML][HTML] Non-invasive assessment of in-vitro embryo quality to improve transfer success

T Rødgaard, PMH Heegaard, H Callesen - Reproductive biomedicine …, 2015 - Elsevier
Although IVF has been performed routinely for many years to help couples with fertility
problems and in relation to modern breeding of farm animals, pregnancy rates after transfer …

A review of the promises and pitfalls of oocyte and embryo metabolomics

L Nel-Themaat, ZP Nagy - Placenta, 2011 - Elsevier
Embryo viability assessment is one of the most important and challenging tasks in IVF.
Evaluation of embryo quality is critical when selecting the best embryo (s) to transfer or …

Day 3 embryo selection by metabolomic profiling of culture medium with near-infrared spectroscopy as an adjunct to morphology: a randomized controlled trial

CG Vergouw, DC Kieslinger, EH Kostelijk… - Human …, 2012 - academic.oup.com
STUDY QUESTION Is the selection of a single Day 3 embryo by metabolomic profiling of
culture medium with near-infrared (NIR) spectroscopy as an adjunct to morphology able to …

Development and evaluation of a live birth prediction model for evaluating human blastocysts from a retrospective study

H Liu, Z Zhang, Y Gu, C Dai, G Shan, H Song, D Li… - Elife, 2023 - elifesciences.org
Background: In infertility treatment, blastocyst morphological grading is commonly used in
clinical practice for blastocyst evaluation and selection, but has shown limited predictive …

Blastulation time measured with time-lapse system can predict in vitro viability of bovine blastocysts

C Huayhua, M Rodríguez, J Vega, M Briones… - PloS one, 2023 - journals.plos.org
The objective of this study was to evaluate the time of blastulation monitored by time-lapse
technology to predict in vitro viability of bovine blastocysts. This technology can be a …