Background: In 2010, this Journal published my comprehensive review of the literature on
hypertrophic scars and keloids. In that article, I presented evidence-based algorithms for the …

Keloid scars, characterized by abnormal fibroproliferation and excessive extracellular matrix
(ECM) production that extends beyond the original wound, often cause pruritus, pain, and …

Background Postoperative scar formation remains a morbidity for patients even with the
advent of minimally invasive techniques. Furthermore, the significant difference between the …

Background: Key risk factors for hypertrophic scarring and surgical-site infections are high-
tension wounds, fat necrosis, and dead space. All could be prevented by appropriate …

Background and purpose Adjuvant electron beam radiation therapy after keloid excision has
been proven as highly effective in reducing local recurrence. We performed a meta-analysis …

Disruption of the molecular pathways during physiological wound healing can lead to raised
scar formation, characterized by rigid, thick scar tissue with associated symptoms of pain …

Background An ideal tension-relieving suture should be efficient for> 3 months to retrieve
normal tensile strength. Most preexisting suturing techniques provided tension elimination …

Background: A universally accepted therapeutic strategy for umbilical keloids has not been
determined. Our team has had considerable success with combination therapy composed of …

Background Surgical excision combined with radiotherapy is considered an effective
treatment for keloids, while the efficacy and safety of this regimen for huge keloids in patients …

Pathological scars (including keloids, hypertrophic scars, and scar contractures) are present
with high severity among certain populations, particularly in Asians and Africans who are …