Astrocyte morphology

KT Baldwin, KK Murai, BS Khakh - Trends in cell biology, 2024 - cell.com
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal
feature of astrocytes is their complex and visually enchanting morphology, referred to as …

Moving beyond the glial scar for spinal cord repair

EJ Bradbury, ER Burnside - Nature communications, 2019 - nature.com
Traumatic spinal cord injury results in severe and irreversible loss of function. The injury
triggers a complex cascade of inflammatory and pathological processes, culminating in …

[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits

J Nagai, X Yu, T Papouin, E Cheong, MR Freeman… - Neuron, 2021 - cell.com
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …

The emerging nature of astrocyte diversity

BS Khakh, B Deneen - Annual review of neuroscience, 2019 - annualreviews.org
Astrocytes are morphologically complex, ubiquitous cells that are viewed as a
homogeneous population tiling the entire central nervous system (CNS). However, this view …

Diversity of astrocyte functions and phenotypes in neural circuits

BS Khakh, MV Sofroniew - Nature neuroscience, 2015 - nature.com
Astrocytes tile the entire CNS. They are vital for neural circuit function, but have traditionally
been viewed as simple, homogenous cells that serve the same essential supportive roles …

Reversible self-assembly of superstructured networks

R Freeman, M Han, Z Álvarez, JA Lewis, JR Wester… - Science, 2018 - science.org
Soft structures in nature, such as protein assemblies, can organize reversibly into functional
and often hierarchical architectures through noncovalent interactions. Molecularly encoding …

Questions and (some) answers on reactive astrocytes

C Escartin, O Guillemaud, M Carrillo‐de Sauvage - Glia, 2019 - Wiley Online Library
Astrocytes are key cellular partners for neurons in the central nervous system. Astrocytes
react to virtually all types of pathological alterations in brain homeostasis by significant …

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

H Konishi, T Okamoto, Y Hara, O Komine… - The EMBO …, 2020 - embopress.org
Microglia are the principal phagocytes that clear cell debris in the central nervous system
(CNS). This raises the question, which cells remove cell debris when microglial phagocytic …

Reactive astrogliosis: A friend or foe in the pathogenesis of Alzheimer's disease

A Kumar, IC Fontana, A Nordberg - Journal of neurochemistry, 2023 - Wiley Online Library
Astrocytes are highly efficient homeostatic glial cells playing a crucial role in optimal brain
functioning and homeostasis. Astrocytes respond to changes in brain homoeostasis …

Reactive astrogliosis: implications in spinal cord injury progression and therapy

X Li, M Li, L Tian, J Chen, R Liu… - Oxidative medicine and …, 2020 - Wiley Online Library
Astrocytes are the most populous glial cells in the central nervous system (CNS). They are
essential to CNS physiology and play important roles in the maintenance of homeostasis …