Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Research on microbial pathogens has traditionally relied on animal and cell culture models
to mimic infection processes in the host. Over recent years, developments in microfluidics …

The female reproductive tract harbours hundreds of bacterial species and produces
numerous metabolites. The uterine cervix is located between the upper and lower parts of …

In silico and experimental approaches have allowed an ever-growing understanding of the
interactions within the microbiota. For instance, recently acquired data have increased …

The global rise of single-use throw-away plastic products has elicited a massive increase in
the nano/microplastics (N/MPLs) exposure burden in humans. Recently, it has been …

The human microbiome orchestrates a variety of metabolic, immunological and regulatory
functions in health and disease. However, experimentally dissecting host–microbiome …

Current biomedical models fail to replicate the complexity of human biology. Consequently,
almost 90% of drug candidates fail during clinical trials after decades of research and …

The human vaginal microbiota has a central role in the regulation of the female reproductive
tract (FRT) inflammation. Indeed, on one hand an optimal environment leading to a …

The maintenance of body homeostasis relies heavily on physiological barriers. Dysfunction
of these barriers can lead to various pathological processes, including increased exposure …

Modulation of the cervix by steroid hormones and commensal microbiome play a central role
in the health of the female reproductive tract. Here we describe organ-on-a-chip (Organ …