Fructus Gardenia (Gardenia jasminoides J. Ellis) phytochemistry, pharmacology of cardiovascular, and safety with the perspective of new drugs development

H Liu, YF Chen, F Li, HY Zhang - Journal of Asian Natural Products …, 2013 - Taylor & Francis
The phytochemistry, cardiovascular pharmacology, toxicology, side effect, and further
development prospects of Gardenia jasminoides J. Ellis (GJE) and its main constituents …

Angong Niuhuang Wan inhibit ferroptosis on ischemic and hemorrhagic stroke by activating PPARγ/AKT/GPX4 pathway

X Bai, E Zheng, L Tong, Y Liu, X Li, H Yang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Angong Niuhuang Wan (AGNHW) is a
prescription from traditional Chinese medicine (TCM) that has been used for centuries to …

Chinese medicine injection qingkailing for treatment of acute ischemia stroke: a systematic review of randomized controlled trials

F Cheng, X Wang, Y Lu, X Zhong… - Evidence‐Based …, 2012 - Wiley Online Library
Qingkailing (QKL) injection was a famous traditional Chinese patent medicine, which was
extensively used to treat the acute stages of cerebrovascular disease. The aim of this study …

Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress‐Induced Apoptosis with a Broad Time Window

F Cheng, X Zhong, Y Lu, X Wang… - Evidence‐Based …, 2012 - Wiley Online Library
In the current study, we are investigating effect of refined QKL on ischemia‐reperfusion‐
induced brain injury in mice. Methods. Mice were employed to induce ischemia‐reperfusion …

Spatiotemporal PET imaging of dynamic metabolic changes after therapeutic approaches of induced pluripotent stem cells, neuronal stem cells, and a Chinese patent …

H Zhang, F Song, C Xu, H Liu, Z Wang… - Journal of Nuclear …, 2015 - Soc Nuclear Med
This study aimed to use spatiotemporal PET imaging to investigate the dynamic metabolic
changes after a combined therapeutic approach of induced pluripotent stem cells (iPSCs) …

Detecting drug–herbal interaction using a spontaneous reporting system database: an example with benzylpenicillin and qingkailing injection

H Li, J Deng, Z Yue, Y Zhang, H Sun - European journal of clinical …, 2015 - Springer
Purpose The study aims to quantify anaphylaxis signal for combined exposure of
benzylpenicilin and qingkailing injection (QI) compared with individual exposure of the two …

Network Pharmacology‐Based Approach to Revealing Biological Mechanisms of Qingkailing Injection against IschemicStroke: Focusing on Blood‐Brain Barrier

S Zhang, X Wang, F Cheng, C Ma, S Fan… - Evidence‐Based …, 2020 - Wiley Online Library
Ischemic stroke is the most common type of cerebrovascular accident worldwide. It causes
long‐term disability and death. Qingkailing (QKL) injection is a traditional Chinese patent …

Polybutylcyanoacrylate nanoparticles for delivering hormone response element-conjugated neurotrophin-3 to the brain of intracerebral hemorrhagic rats

CY Chung, JT Yang, YC Kuo - Biomaterials, 2013 - Elsevier
Hypertensive intracerebral hemorrhage (ICH) is a rapidly evolutional pathology, inducing
necrotic cell death followed by apoptosis, and alters gene expression levels in surrounding …

[HTML][HTML] Pre-treatment with a Xingnaojing preparation ameliorates sevoflurane-induced neuroapoptosis in the infant rat striatum

ZJ Yang, YW Wang, CL Li… - Molecular medicine …, 2015 - spandidos-publications.com
Xingnaojing (XNJ), is a standardized Chinese herbal medicine product derived from An
Gong Niu Huang Pill. It may be involved in neuroprotection in a number of neurological …

Outcome-dependent global similarity analysis of imbalanced core signaling pathways in ischemic mouse hippocampus

J Liu, Z Zhang, C Zhou, Y Wang… - CNS & Neurological …, 2012 - ingentaconnect.com
Analysis of the diverse interactions of multiple signaling pathways is an emerging challenge
in the era of networking pharmacology. To reveal imbalanced signaling pathways and …