Applications of charge detection mass spectrometry in molecular biology and biotechnology

MF Jarrold - Chemical reviews, 2021 - ACS Publications
Charge detection mass spectrometry (CDMS) is a single-particle technique where the
masses of individual ions are determined from simultaneous measurement of their mass-to …

Virus‐like particles: Next‐generation nanoparticles for targeted therapeutic delivery

MJ Rohovie, M Nagasawa… - … & translational medicine, 2017 - Wiley Online Library
Most drug therapies distribute the agents throughout the entire body, even though the drugs
are typically only needed at specific tissues. This often limits dosage and causes discomfort …

Bioengineered protein-based nanocage for drug delivery

EJ Lee, NK Lee, IS Kim - Advanced drug delivery reviews, 2016 - Elsevier
Nature, in its wonders, presents and assembles the most intricate and delicate protein
structures and this remarkable phenomenon occurs in all kingdom and phyla of life. Of these …

On virus growth and form

R Zandi, B Dragnea, A Travesset, R Podgornik - Physics Reports, 2020 - Elsevier
We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Engineering self-assembling protein nanoparticles for therapeutic delivery

A Olshefsky, C Richardson, SH Pun… - Bioconjugate …, 2022 - ACS Publications
Despite remarkable advances over the past several decades, many therapeutic
nanomaterials fail to overcome major in vivo delivery barriers. Controlling immunogenicity …

Nanoreactors by programmed enzyme encapsulation inside the capsid of the bacteriophage P22

DP Patterson, PE Prevelige, T Douglas - ACS nano, 2012 - ACS Publications
The virus like particle (VLP) derived from bacteriophage P22 presents a unique platform for
constructing catalytically functional nanomaterials by encapsulation of enzymes into its …

Bioinspired approaches to self-assembly of virus-like particles: From molecules to materials

Y Wang, T Douglas - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus When viewed through the lens of materials science, nature provides a vast
library of hierarchically organized structures that serve as inspiration and raw materials for …

Genetically Engineered Viral Vectors and Organic‐Based Non‐Viral Nanocarriers for Drug Delivery Applications

S Hajebi, S Yousefiasl, I Rahimmanesh… - Advanced …, 2022 - Wiley Online Library
Conventional drug delivery systems are challenged by concerns related to systemic toxicity,
repetitive doses, drug concentrations fluctuation, and adverse effects. Various drug delivery …

Protein cages and synthetic polymers: a fruitful symbiosis for drug delivery applications, bionanotechnology and materials science

M Rother, MG Nussbaumer, K Renggli… - Chemical Society …, 2016 - pubs.rsc.org
Protein cages are hollow protein nanoparticles, such as viral capsids, virus-like particles,
ferritin, heat-shock proteins and chaperonins. They have well-defined capsule-like structures …

Functionalization of protein-based nanocages for drug delivery applications

L Schoonen, JCM van Hest - Nanoscale, 2014 - pubs.rsc.org
Traditional drug delivery strategies involve drugs which are not targeted towards the desired
tissue. This can lead to undesired side effects, as normal cells are affected by the drugs as …