Copper active sites in biology

EI Solomon, DE Heppner, EM Johnston… - Chemical …, 2014 - ACS Publications
On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

Aerobic copper-catalyzed organic reactions

SE Allen, RR Walvoord, R Padilla-Salinas… - Chemical …, 2013 - ACS Publications
The chemistry of copper is extremely rich because it can easily access Cu0, CuI, CuII, and
CuIII oxidation states allowing it to act through one-electron or two-electron processes. As a …

A lysine–cysteine redox switch with an NOS bridge regulates enzyme function

M Wensien, FR von Pappenheim, LM Funk… - Nature, 2021 - nature.com
Disulfide bonds between cysteine residues are important post-translational modifications in
proteins that have critical roles for protein structure and stability, as redox-active catalytic …

Crystal Structure of Agaricus bisporus Mushroom Tyrosinase: Identity of the Tetramer Subunits and Interaction with Tropolone

WT Ismaya, HJ Rozeboom, A Weijn, JJ Mes… - Biochemistry, 2011 - ACS Publications
Tyrosinase catalyzes the conversion of phenolic compounds into their quinone derivatives,
which are precursors for the formation of melanin, a ubiquitous pigment in living organisms …

Multicopper oxidases and oxygenases

EI Solomon, UM Sundaram, TE Machonkin - Chemical reviews, 1996 - ACS Publications
Copper is an essential trace element in living systems, present in the parts per million
concentration range. It is a key cofactor in a diverse array of biological oxidation-reduction …

Structural and functional aspects of metal sites in biology

RH Holm, P Kennepohl, EI Solomon - Chemical reviews, 1996 - ACS Publications
The field of bioinorganic chemistry is at a propitious stage of development. Ever more
complex metallobiomolecules are isolated and purified, physical methodologies and …

C H Bond Activation in Transition Metal Species from a Computational Perspective

D Balcells, E Clot, O Eisenstein - Chemical reviews, 2010 - ACS Publications
Alkanes constitute the cheapest and most abundant feedstock for organic chemicals.
However, the redistribution of CsC and CsH bonds in hydrocarbons into more sophisticated …

Biologically inspired oxidation catalysis

L Que Jr, WB Tolman - Nature, 2008 - nature.com
The development of processes for selective hydrocarbon oxidation is a goal that has long
been pursued. An additional challenge is to make such processes environmentally friendly …

Synthetic Fe/Cu complexes: toward understanding heme-copper oxidase structure and function

SM Adam, GB Wijeratne, PJ Rogler, DE Diaz… - Chemical …, 2018 - ACS Publications
Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

Biochemistry of methanogenesis: a tribute to Marjory Stephenson: 1998 Marjory Stephenson prize lecture

RK Thauer - Microbiology, 1998 - microbiologyresearch.org
Max-Planck-Institut für terrestrische Mikrobiologie, Karl-von-Frisch-Straße, D-35043
Marburg, and Laboratorium für Mikrobiologie, Fachbereich Biologie, Philipps-Universität …