Advancing conventional open‐loop DBS as a therapy for PD is crucial for overcoming
important issues such as the delicate balance between beneficial and adverse effects and …

Deep brain stimulation (DBS) is a successful treatment for patients with Parkinson's disease.
In adaptive DBS, stimulation is titrated according to feedback about clinical state and …

Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …

Objectives To investigate the long term association of subthalamic beta activity with
parkinsonian motor signs. Methods We recruited 15 patients with Parkinson's disease …

Deep brain stimulation (DBS) treatment has proven effective in suppressing symptoms of
rigidity, bradykinesia, and tremor in Parkinson's disease. Still, patients may suffer from …

Objective Deep brain stimulation (DBS) allows for direct recordings of neuronal activity from
the human basal ganglia. In Parkinson's disease, a disease‐specific physiomarker was …

Sleep disturbance is a prevalent and disabling comorbidity in Parkinson's disease (PD). We
performed multi-night (n= 57) at-home intracranial recordings from electrocorticography and …

Objective. Deep brain stimulation (DBS) is an established and valid therapy for a variety of
pathological conditions ranging from motor to cognitive disorders. Still, much of the DBS …

This study compares the effects on motor symptoms between conventional deep brain
stimulation (cDBS) and closed-loop adaptive deep brain stimulation (aDBS) in patients with …

Background Abnormal beta band activity in the subthalamic nucleus (STN) is known to be
exaggerated in patients with Parkinson's disease, and the amplitude of such activity has …