During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

The term placental bed was coined to describe the maternal-fetal interface (ie, the area in
which the placenta attaches itself to the uterus). Appropriate vascularization of this area is of …

Pre-eclampsia is characterized by new-onset hypertension and proteinuria at≥ 20 weeks of
gestation. In the absence of proteinuria, hypertension together with evidence of systemic …

BACKGROUND Miscarriage is the spontaneous loss of a pregnancy before 12 weeks (early
miscarriage) or from 12 to 24 weeks (late miscarriage) of gestation. Miscarriage occurs in …

Defective deep placentation has been associated with a spectrum of complications of
pregnancy including preeclampsia, intrauterine growth restriction, preterm labor, preterm …

Failure to transform uteroplacental spiral arteries is thought to underpin disorders of
pregnancy, including preeclampsia and fetal growth restriction (FGR). In this study, spiral …

BACKGROUND Recurrent miscarriage and pre-eclampsia are common reproductive
disorders, but their causes are often unknown. Recent evidence has provided new insight …

Uterine spiral artery remodeling is required for successful human pregnancy; impaired
remodeling is associated with pregnancy complications, including late miscarriage …

Objective To investigate whether a significant association between vitamin D status and the
risk of miscarriage or recurrent miscarriage (RM) exists. Design Systematic review and meta …

Background The major challenge for obstetrics is the prediction and prevention of the great
obstetrical syndromes. We propose that defining obstetrical diseases by the combination of …