Oxidative stress may be defined as an imbalance between reactive oxygen species (ROS)
and the antioxidant system to counteract or detoxify these potentially damaging molecules …

Reactive oxygen species (ROS) are radical oxygen intermediates that serve as important
second messengers in signal transduction. However, when the accumulation of these …

Familial hypercholesterolemia (FH) is a metabolic condition caused mainly by a mutation in
the low-density lipoprotein (LDL) receptor gene (LDLR), which is highly prevalent in the …

Familial hypercholesterolemia (FH) is a genetic disease characterized by high low-density
lipoprotein (LDL) cholesterol (LDL-c) concentrations that increase cardiovascular risk and …

Primary hypercholesterolemia, a metabolic disorder characterized by elevated circulating
levels of cholesterol products, mainly low-density lipoproteins, is associated with …

Background: Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder
characterizied by elevated levels of circulating low-density lipoprotein cholesterol (LDL-C) …

Familial hypercholesterolemia (FH) is a genetic disorder characterized by high serum levels
of low‐density lipoprotein cholesterol (LDL‐c). FH is characterized by accelerated …

Atherosclerosis (AS) manifested by lipid accumulation, extracellular matrix protein
deposition, and calcification in the intima and media of the large to medium size arteries …

Aims Subjects with familial hypercholesterolemia (FH) are characterized by an increased
amount of low-density lipoprotein cholesterol (LDL-C) that promotes a continuous …

Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors are a novel group of
hypolipidemic drugs that are recommended particularly for high-risk hypercholesterolemia …