Background: Cancer, an uncontrolled multistage disease causing swift division of cells, is a
leading disease with the highest mortality rate. Cellular heterogeneity, evading growth …

Fucoidan is a dietary brown algae-derived fucose-rich polysaccharide. However, the
anticancer effects of fucoidan for oral cancer treatment remain unclear, particularly in terms …

Background: Lichens are a composite consortium of a fungus and an alga. The symbiotic
organisms are naturally equipped with distinct characteristics as compared to constituting …

Lichen metabolites represent a wide range of substances with a variety of biological effects.
The present study was designed to analyze the potential antiproliferative, antimicrobial and …

Oral squamous cell carcinoma (OSCC) is the most frequent oral malignancy, with a high
death rate and an inadequate response to conventional chemotherapeutic drugs. Medical …

Lichens represent an important resource for common traditional medicines due to their
numerous metabolites that can exert diverse pharmacological activities including anticancer …

Nowadays, numerous biomedical studies performed on natural compounds and plant
extracts aim to obtain highly selective pharmacological activities without unwanted toxic …

Increased neddylation benefits the survival of several types of cancer cells. The inhibition of
neddylation has the potential to exert anticancer effects but is rarely assessed in oral cancer …

The oral cavity's common pathologies are tooth decay, periodontal disease, and oral cancer;
oral squamous cell carcinoma (OSCC) is the most frequent oral malignancy, with a high …

Usnea genus (Parmeliaceae, lichenized Ascomycetes) is a potent phytomedicine, due to
phenolic secondary metabolites, with various pharmacological effects. Therefore, our study …