The characteristic molecular composition of the different glycosaminoglycans (GAGs) is
related to their role as structural components and regulators of a multitude of functions of …

The current technology available for surface microfabrication with macromolecules to
regulate cell functions is reviewed. Surface topology, and surface modification with …

Photoactivatable ligands are important tools used in drug discovery and drug development.
These ligands enable researchers to identify the targets of durgs, to determine the affinity …

A novel method for patterning cellular co-cultures that uses the layer-by-layer deposition of
ionic biopolymers is described. Non-biofouling hyaluronic acid (HA) micropatterns were …

Polyetheretherketone (PEEK) is a promising implant material because of its excellent
mechanical characteristics. Although this polymer is a standard material in spinal …

Animal cells live in environments where many of the features that surround them are on the
nanoscale, for example detail on collagen molecules. Do cells react to objects of this size …

Previous studies on customizing cell culture environments have utilized a variety of
microfabrication‐based tools to control the spatial localization of adhesive proteins and …

Because cell shape and alignment, cell–matrix adhesion, and cell–cell contact can all affect
growth, and because mechanical strains in vivo are multiaxial and anisotropic, we …

The possibility to replace damaged or diseased organs with artificial tissues engineered
from a combination of living cells and biocompatible scaffolds is becoming a reality through …

The precise contribution of different CS-GAGs to CSPG-mediated inhibition of axonal growth
after CNS injury is unknown. Quantification of the CS-GAGs in uninjured and injured brain …