Polymeric micelles for anticancer drug delivery

N Majumder, NG Das, SK Das - Therapeutic delivery, 2020 - Taylor & Francis
Polymeric micelles have gained interest as novel drug delivery systems for the treatment
and diagnosis of cancer, as they offer several advantages over conventional drug therapies …

Polymeric mixed micelles as nanomedicines: Achievements and perspectives

M Cagel, FC Tesan, E Bernabeu, MJ Salgueiro… - European Journal of …, 2017 - Elsevier
During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …

The use of TPGS in drug delivery systems to overcome biological barriers

MT Luiz, LD Di Filippo, RC Alves, VHS Araújo… - European Polymer …, 2021 - Elsevier
Nanotechnology has been applied in the medicine field to improve the treatment of a wide
range of diseases. However, to reach the nanomedicines delivery to desirable target tissue …

Nanoengineered drug delivery systems for enhancing antibiotic therapy

RS Kalhapure, N Suleman, C Mocktar, N Seedat… - Journal of …, 2015 - Elsevier
Formulation scientists are recognizing nanoengineered drug delivery systems as an
effective strategy to overcome limitations associated with antibiotic drug therapy. Antibiotics …

Novel Soluplus®—TPGS mixed micelles for encapsulation of paclitaxel with enhanced in vitro cytotoxicity on breast and ovarian cancer cell lines

E Bernabeu, L Gonzalez, M Cagel, EP Gergic… - Colloids and Surfaces B …, 2016 - Elsevier
The aim of this work was to develop mixed micelles based on two biocompatible copolymers
of polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol (Soluplus®) and D-α …

Polymeric nanomedicines for poorly soluble drugs in oral delivery systems: An update

X Ma, RO Williams III - Journal of pharmaceutical investigation, 2018 - Springer
The field of nanomedicine offers promising new drug delivery systems with enhanced
properties. The literature has reported on the development of various nanomedicines that …

Pulmonary delivery of rifampicin-loaded soluplus micelles against Mycobacterium tuberculosis

E Grotz, NL Tateosian, J Salgueiro, E Bernabeu… - Journal of Drug Delivery …, 2019 - Elsevier
Tuberculosis (TB) stands as the second “most deadly infectious disease” behind AIDS.
Rifampicin (RIF) represents one of the most effective anti-TB drugs of the “short-term” oral TB …

[HTML][HTML] D-ɑ-tocopheryl polyethylene glycol succinate: a review of multifarious applications in nanomedicines

PS Kumbhar, S Nadaf, AS Manjappa, NK Jha… - OpenNano, 2022 - Elsevier
Role of excipients in designing diverse dosage forms has been highly acclaimed and needs
no introduction. These are integral components of pharmaceutical formulations and …

Mixed micelles for encapsulation of doxorubicin with enhanced in vitro cytotoxicity on breast and ovarian cancer cell lines versus Doxil®

M Cagel, E Bernabeu, L Gonzalez… - Biomedicine & …, 2017 - Elsevier
Doxorubicin (DOX) is used as a “first-line” antineoplastic drug in ovarian and metastatic
breast cancer. However, serious side effects, such as cardiotoxicity have been reported after …

Preparation, evaluation and metabolites study in rats of novel amentoflavone-loaded TPGS/soluplus mixed nanomicelles

X Feng, Y Chen, L Li, Y Zhang, L Zhang, Z Zhang - Drug delivery, 2020 - Taylor & Francis
Amentoflavone (AMF) is a kind of biflavonoids existing in Ginkgo biloba leaves. It has many
biological activities, such as antioxidant, anti-inflammatory, anti-bacterial, antiviral …