Comprehensive overview of carboxamide derivatives as succinate dehydrogenase inhibitors

B Luo, Y Ning - Journal of Agricultural and Food Chemistry, 2022 - ACS Publications
Up to now, a total of 24 succinate dehydrogenase inhibitors (SDHIs) fungicides have been
commercialized, and SDHIs fungicides were also one of the most active fungicides …

New oxadiazole/triazole derivatives with antimicrobial and antioxidant properties

S Dawbaa, D Nuha, AE Evren, MY Cankiliç… - Journal of Molecular …, 2023 - Elsevier
In the search for new antimicrobial agents, we synthesized a new series of oxadiazole and
triazole derivatives. The series of N-(benzothiazol-2-yl)-2-{{5-[(2-chlorophenoxy) methyl]-1 …

Design, synthesis, and fungicidal evaluation of novel 1, 3-benzodioxole-pyrimidine derivatives as potential succinate dehydrogenase inhibitors

Y Sun, Z Yang, Q Liu, X Sun, L Chen… - Journal of Agricultural …, 2022 - ACS Publications
A series of novel 1, 3-benzodioxole-pyrimidine derivatives were designed and synthesized.
The in vitro bioassay indicated that compounds 4e, 4g, 4n, 5c, and 5e displayed excellent …

Rational design, synthesis, and biological evaluation of fluorine-and chlorine-substituted pyrazol-5-yl-benzamide derivatives as potential succinate dehydrogenase …

W Wang, J Wang, J Wu, M Jin, J Li, S Jin… - Journal of Agricultural …, 2022 - ACS Publications
To develop novel succinate dehydrogenase inhibitors (SDHIs), two series of novel N-4-
fluoro-pyrazol-5-yl-benzamide and N-4-chloro-pyrazol-5-yl-benzamide derivatives were …

Oxime chemistry in crop protection

C Lamberth - Pest Management Science, 2024 - Wiley Online Library
An overview is given on the significance of the oxime moiety in crop protection chemistry.
This review focuses on the two most important aspects of agrochemical oximes, which are …

Rational exploration of novel SDHI fungicide through an amide-β-ketonitrile bioisosteric replacement strategy

C Zhou, X Sun, W Fu, Z Li, J Cheng… - Journal of Agricultural …, 2023 - ACS Publications
The identification of succinate dehydrogenase inhibitor (SDHI) fungicides bearing a novel
scaffold is of great importance to control pathogenic fungi. Difluoromethyl-pyrazole β …

Novel pyrazole carboxamide containing a diarylamine scaffold potentially targeting fungal succinate dehydrogenase: antifungal activity and mechanism of action

Y Zhao, A Zhang, X Wang, K Tao, H Jin… - Journal of Agricultural …, 2022 - ACS Publications
Succinate dehydrogenase (SDH) is known as an ideal target for the development of novel
fungicides. Over the years, a series of novel pyrazole carboxamides containing a …

Design, synthesis, and biological evaluation of novel pyrazol-5-yl-benzamide derivatives containing oxazole group as potential succinate dehydrogenase inhibitors

X Cheng, Z Xu, H Luo, X Chang… - Journal of Agricultural and …, 2022 - ACS Publications
A series of pyrazol-5-yl-benzamide derivatives containing the oxazole group were designed
and synthesized as potential SDH inhibitors. According to the results of the bioassays, most …

Discovery of novel pyrazol-5-yl-benzamide derivatives containing a thiocyanato group as broad-spectrum fungicidal candidates

Y Li, H Yang, Y Ma, Y Cao, D Xu, X Liu… - Journal of Agricultural …, 2023 - ACS Publications
In an effort to promote the development of new fungicides, a series of 48 novel N-(1-methyl-4-
thiocyanato-1 H-pyrazol-5-yl)-benzamide derivatives A1–A36 and B1–B12 were designed …

Novel camphor sulfonohydrazide and sulfonamide derivatives as potential succinate dehydrogenase inhibitors against phytopathogenic fungi/oomycetes

Z Yang, X Sun, D Jin, Y Qiu, L Chen… - Journal of Agricultural …, 2022 - ACS Publications
To discover novel fungicidal agrochemicals for treating wheat scab, 39 novel camphor
sulfonohydrazide/sulfonamide derivatives 4a–4t and 6a–6s were designed and synthesized …