Circular RNAs (circRNAs) are a new class of non-coding RNAs formed by covalently closed
loops through backsplicing. Recent methodologies have enabled in-depth characterization …

Although it was long thought that eukaryotic translation almost always initiates at an AUG
start codon, recent advancements in ribosome footprint mapping have revealed that non …

Translation is one of the fundamental processes of life. It comprises the assembly of
polypeptides whose amino acid sequence corresponds to the codon sequence of an …

In trypanosomes, RNA polymerase II transcription is polycistronic and individual mRNAs are
excised by trans-splicing and polyadenylation. The lack of individual gene transcription …

Viruses must co-opt the cellular translation machinery to produce progeny virions.
Eukaryotic viruses have evolved a variety of ways to manipulate the cellular translation …

Changes in gene expression are at the core of most biological processes, from cell
differentiation to organ development, including the adaptation of the whole organism to the …

Circular RNAs a kind of covalently closed RNA and widely expressed in eukaryotes.
CircRNAs are involved in a variety of physiological and pathological processes, but their …

Adequate reprogramming of cellular metabolism in response to stresses or suboptimal
growth conditions involves a myriad of coordinated changes that serve to promote cell …

Gene expression universally relies on protein synthesis, where ribosomes recognize and
decode the messenger RNA template by cycling through translation initiation, elongation …

Cellular stress is an intrinsic part of cell physiology that underlines cell survival or death. The
ability of mammalian cells to regulate global protein synthesis (aka translational control) …