Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation

C Lavialle, G Cornelis, A Dupressoir… - … of the Royal …, 2013 - royalsocietypublishing.org
The development of the emerging field of 'paleovirology'allows biologists to reconstruct the
evolutionary history of fossil endogenous retroviral sequences integrated within the genome …

The cytokine/chemokine response in Leishmania/HIV infection and co-infection

S Maksoud, J El Hokayem - Heliyon, 2023 - cell.com
HIV infection progressively weakens the immune system by infecting and destroying cells
involved in host defense. Viral infection symptoms are generated and aggravated as …

HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim

P Castellano, L Prevedel, EA Eugenin - Scientific reports, 2017 - nature.com
While HIV kills most of the cells it infects, a small number of infected cells survive and
become latent viral reservoirs, posing a significant barrier to HIV eradication. However, the …

Remodeling of the host cell plasma membrane by HIV-1 Nef and Vpu: a strategy to ensure viral fitness and persistence

SM Sugden, MG Bego, TNQ Pham, ÉA Cohen - Viruses, 2016 - mdpi.com
The plasma membrane protects the cell from its surroundings and regulates cellular
communication, homing, and metabolism. Not surprisingly, the composition of this …

Necroptosis Takes Place in Human Immunodeficiency Virus Type-1 (HIV-1)-Infected CD4+ T Lymphocytes

T Pan, S Wu, X He, H Luo, Y Zhang, M Fan, G Geng… - PloS one, 2014 - journals.plos.org
Human immunodeficiency virus type 1 (HIV-1) infection is characterized by progressive
depletion of CD4+ T lymphocytes and dysfunction of the immune system. The numbers of …

Cell fusion and syncytium formation in betaherpesvirus infection

J Tang, G Frascaroli, X Zhou, J Knickmann, W Brune - Viruses, 2021 - mdpi.com
Cell–cell fusion is a fundamental and complex process that occurs during reproduction,
organ and tissue growth, cancer metastasis, immune response, and infection. All enveloped …

Syncytial apoptosis signaling network induced by the HIV-1 envelope glycoprotein complex: an overview

R Nardacci, JL Perfettini, L Grieco, D Thieffry… - Cell death & …, 2015 - nature.com
Infection by human immunodeficiency virus-1 (HIV-1) is associated with a progressive
decrease in CD4 T-cell numbers and the consequent collapse of host immune defenses …

The role of tetraspanins in fusion

M Fanaei, PN Monk, LJ Partridge - Biochemical Society …, 2011 - portlandpress.com
Membrane fusion underlies such important biological processes as virus entry into host
cells, intracellular protein trafficking, fertilization, formation of muscle fibres and bone …

Leishmania donovani and HIV co-infection in vitro: Identification and characterization of main molecular players

S Maksoud, JT Ortega, M Hidalgo, HR Rangel - Acta Tropica, 2022 - Elsevier
The incidence of Leishmania/HIV co-infection is growing and few studies detail the cellular
processes and macromolecules participating in co-infection. Thus, the goal of this study was …

HIV-1 V3 loop crown epitope-focused mimotope selection by patient serum from random phage display libraries: Implications for the epitope structural features

KG Gazarian, Y Palacios-Rodríguez, TG Gazarian… - Molecular …, 2013 - Elsevier
The crown region of the V3 loop in HIV-1 that contains the conserved amino acid sequence
GPGR/G is known as the principal neutralizing determinant due to the extraordinary ability of …