Type 2 diabetes and cognitive dysfunction are highly prevalent disorders worldwide.
Although type 2 diabetes is associated with an increased risk of dementia, awareness of the …

Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …

Abstract Aims The Valve Academic Research Consortium (VARC), founded in 2010, was
intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these …

Background The efficacy of closure of a patent foramen ovale (PFO) in the prevention of
recurrent stroke after cryptogenic stroke is uncertain. We investigated the effect of PFO …

Importance It is unclear whether female carriers of the apolipoprotein E (APOE) ε4 allele are
at greater risk of developing Alzheimer disease (AD) than men, and the sex-dependent …

Alzheimer's disease (AD) is a progressive neurodegenerative disease marked by deficits in
episodic memory, working memory (WM), and executive function. Examples of executive …

The construct of mild cognitive impairment (MCI) has evolved over the past 10 years since
the publication of the new MCI definition at the K ey S ymposium in 2003, but the core …

Despite the global impact and advances in understanding the pathophysiology of
cerebrovascular diseases, the term “stroke” is not consistently defined in clinical practice, in …

Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Accumulating evidence points to a link between age-related hearing loss and cognitive
decline, but their relationship is not clear. Does one cause the other, or does some third …