The serine proteases of the trypsin-like (S1) family play critical roles in many key biological
processes including digestion, blood coagulation, and immunity. Members of this family …

Virtually all recombinant proteins are now prepared using fusion domains also known as
“tags”. The use of tags helps to solve some serious problems: to simplify procedures of …

Introduction 3. Gene and protein structure 3.1. Proenteropeptidase gene 3.2.
Proenteropeptidase domain structure 4. Biosynthesis and trafficking 4.1. Localization of …

Enteropeptidase is a serine protease used in different biotechnological applications. For
many applications the smaller light chain can be used to avoid the expression of the rather …

Proteases are widely used in analytical sciences and play a central role in several
widespread diseases. Thus, there is an immense need for highly adaptable and sensitive …

Enterokinase is an ideal tool protease for cleaving fusion proteins in genetic engineering.
The bovine enterokinase light chain (bEK L) produced in Pichia pastoris was shown to be a …

Background Enteropeptidase (EP) is a type II transmembrane serine protease and a
physiological activator of trypsinogen. Extensive studies related to EP have been conducted …

Human growth hormone (hGH) was one of the first recombinant proteins approved for the
treatment of human growth disorders. Its small size (191 amino acids), possession of only 2 …

Enterokinase is one of the hydrolases that catalyze hydrolysis to regulate biological
processes in intestinal visceral mucosa. Enterokinase plays an essential role in accelerating …

Human enterokinase (enteropeptidase, rhEP), a serine protease expressed in the proximal
part of the small intestine, converts the inactive form of trypsinogen to active trypsin by …