The advent of immunotherapy has made an indelible mark on the field of cancer therapy,
especially the application of immune checkpoint inhibitors in clinical practice. Although …

Adenosine is an endogenous nucleoside that regulates many physiological and
pathological processes. It is derived from either the intracellular or extracellular …

CD73, a cell surface-bound nucleotidase, serves as a crucial metabolic and immune
checkpoint. Several studies have shown that CD73 is widely expressed on immune cells …

CD73, an ectoenzyme responsible for adenosine production, is often elevated in immuno-
suppressive tumor environments. Inhibition of CD73 activity holds great promise as a …

Abstract Background Mitochondrial transplantation (MTx) has emerged as a novel
therapeutic strategy, particularly effective in diseases characterized by mitochondrial …

Renal cell carcinoma (RCC), especially clear cell RCC, is generally considered an
immunotherapy-responsive cancer. Recently, the prognosis for patients with locally …

B cells have emerged as central players in the tumor microenvironment (TME) of non-small
cell lung cancer (NSCLC). However, although there is clear evidence for their involvement in …

Pancreatic cancer is a major cause of cancer-related death, but despondently, the outlook
and prognosis for this resistant type of tumor have remained grim for a long time. Currently, it …

Simple Summary CD73 and adenosine are garnering significant attention in lung cancer
research. CD73, an enzyme crucial for adenosine production, is found in various cells …

Immune-related drug delivery systems (DDSs) in humanized mouse models are at the
forefront of cancer research and serve as bridges between preclinical studies and clinical …