Currently, neurodegenerative diseases are a major cause of disability around the world.
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …

Investigations of the effect of antioxidants on idiopathic Parkinson's disease have been
unsuccessful because the preclinical models used to propose these clinical studies do not …

Parkinson's disease (PD) is a complex neurological disorder characterized by motor and
nonmotor features. Although some drugs have been developed for the therapy of PD in a …

Compensatory mechanisms that augment dopamine (DA) signaling are thought to mitigate
onset of hypokinesia prior to major loss of tyrosine hydroxylase (TH) in striatum that occurs …

Objectives Parkinson's disease (PD) is the second most common neurodegenerative
disease. Chlorogenic acid (CGA) is a polyphenolic substance derived from various …

Dopaminergic degeneration is a central feature of Parkinson's disease (PD), but glial
dysfunction may accelerate or trigger neuronal death. In fact, astrocytes play a key role in the …

Increasing evidence suggests that the gut–brain axis plays a crucial role in Parkinson's
disease (PD). The abnormal accumulation of aggregated alpha-synuclein (aSyn) in the …

Nutraceuticals have been extensively studied worldwide due to its neuroprotective effects in
in vivo and in vitro studies, attributed by the antioxidative properties. Alzheimer (AD) and …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons in the substantia nigra that results in a decrease in dopamine levels …

Purpose To develop a deep learning–based approach to reduce the scan time of multipool
CEST MRI for Parkinson's disease (PD) while maintaining sufficient prediction accuracy …