Tackling antibiotic resistance with compounds of natural origin: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán, V Micol - Biomedicines, 2020 - mdpi.com
Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …

Immunoliposomes: A review on functionalization strategies and targets for drug delivery

JO Eloy, R Petrilli, LNF Trevizan, M Chorilli - Colloids and Surfaces B …, 2017 - Elsevier
Nanoparticles, especially liposomes, have gained prominence in the field of drug delivery
for the treatment of human diseases, particularly cancer; they provide several advantages …

Melittin: a venom-derived peptide with promising anti-viral properties

H Memariani, M Memariani, H Moravvej… - European Journal of …, 2020 - Springer
Despite tremendous advances in the development of anti-viral therapeutics, viral infections
remain a chief culprit accounting for ongoing morbidity and mortality worldwide. Natural …

Melittin-based nano-delivery systems for cancer therapy

A Wang, Y Zheng, W Zhu, L Yang, Y Yang, J Peng - Biomolecules, 2022 - mdpi.com
Melittin (MEL) is a 26-amino acid polypeptide with a variety of pharmacological and
toxicological effects, which include strong surface activity on cell lipid membranes, hemolytic …

Pharmacological synergism of bee venom and melittin with antibiotics and plant secondary metabolites against multi-drug resistant microbial pathogens

ALA Issam, S Zimmermann, J Reichling, M Wink - Phytomedicine, 2015 - Elsevier
The goal of this study was to investigate the antimicrobial activity of bee venom and its main
component, melittin, alone or in two-drug and three-drug combinations with antibiotics …

Immunoliposome encapsulation increases cytotoxic activity and selectivity of curcumin and resveratrol against HER2 overexpressing human breast cancer cells

A Catania, E Barrajón-Catalán, S Nicolosi… - Breast cancer research …, 2013 - Springer
Natural compounds have been studied as a source of countless bioactive compounds with
diverse activities. Among them, many dietary phytochemicals have been thoroughly studied …

Antimicrobial peptide melittin against Xanthomonas oryzae pv. oryzae, the bacterial leaf blight pathogen in rice

W Shi, C Li, M Li, X Zong, D Han, Y Chen - Applied Microbiology and …, 2016 - Springer
Xanthomonas oryzae pv. oryzae is a destructive bacterial disease of rice, and the
development of an environmentally safe bactericide is urgently needed. Antimicrobial …

[HTML][HTML] Leveraging immunoliposomes as nanocarriers against SARS-CoV-2 and its emerging variants

NDFM Faizal, NA Ramli, NNIM Rani, NA Shaibie… - Asian Journal of …, 2023 - Elsevier
The global COVID-19 pandemic arising from SARS-CoV-2 has impacted many lives, gaining
interest worldwide ever since it was first identified in December 2019. Till 2023, 752 million …

Bio-nano scale modifications of melittin for improving therapeutic efficacy

M Akbarzadeh-Khiavi, M Torabi, AH Olfati… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Melittin (MLT), a natural membrane-active component, is the most prominent
cytolytic peptide from bee venom. Remarkable biological properties of MLT, including anti …

Nanodelivery systems as new tools for immunostimulant or vaccine administration: targeting the fish immune system

J Ji, D Torrealba, À Ruyra, N Roher - Biology, 2015 - mdpi.com
Fish disease treatments have progressed significantly over the last few years and have
moved from the massive use of antibiotics to the development of vaccines mainly based on …