Much success has been achieved with platinum-based chemotherapeutic agents, ie through
interactions with DNA. The long-term application of Pt complexes is thwarted by issues …

The discovery of cisplatin (cis-Pt (NH 3) 2 Cl 2) as an antineoplastic agent has focussed
attention on the rational design of metal complexes that can be potentially used in cancer …

With the highest incidence, breast cancer is the leading cause of cancer deaths among
women in the world. Tumor metastasis is the major contributor of high mortality in breast …

This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …

Based on the chemotherapeutic success of cisplatin, carboplatin and oxaliplatin as
anticancer drugs, and silver sulfadiazine (AgSDZ) as an antibacterial drug, exploration of the …

Cancer stem cells (CSCs) are heavily linked to fatal incidences of cancer relapse and
metastasis. Conventional cancer therapies such as surgery, chemotherapy and radiation are …

Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in
2020. Palladium complexes can be used as anticancer and pharmacological agents as a …

Background: Phospholipases D1 and D2 (PLD1/2) hydrolyse cell membrane
glycerophospholipids to generate phosphatidic acid, a signalling lipid, which regulates cell …

A series of bis-salicylaldimine ligands bearing two ON-donor functions were reacted with
dichloro (p-cymene) ruthenium (II) dimer in the presence of base (NaOAc) and a series of …

The reactions of picolinyl and 4-chloropicolinyl chlorides with methyl esters of S-methyl-l-
cysteine, l-and d-methionine, and l-histidine afforded a series of functionalized …