Bridging nanoplatform and vaccine delivery, a landscape of strategy to enhance nasal immunity

Z Teng, LY Meng, JK Yang, Z He, XG Chen… - Journal of Controlled …, 2022 - Elsevier
Vaccination is an urgently needed and effective option to address epidemic, cancers,
allergies, and other diseases. Nasal administration of vaccines offers many benefits over …

Oral mucosa immunity: ultimate strategy to stop spreading of pandemic viruses

H Jang, M Matsuoka, M Freire - Frontiers in Immunology, 2023 - frontiersin.org
Global pandemics are most likely initiated via zoonotic transmission to humans in which
respiratory viruses infect airways with relevance to mucosal systems. Out of the known …

Rational development of a combined mRNA vaccine against COVID-19 and influenza

Q Ye, M Wu, C Zhou, X Lu, B Huang, N Zhang, H Zhao… - npj Vaccines, 2022 - nature.com
As the world continues to experience the COVID-19 pandemic, seasonal influenza remain a
cause of severe morbidity and mortality globally. Worse yet, coinfection with SARS-CoV-2 …

Oil-in-ionic liquid nanoemulsion-based intranasal delivery system for influenza split-virus vaccine

X Lin, Y Sheng, X Zhang, Z Li, Y Yang, J Wu… - Journal of Controlled …, 2022 - Elsevier
Effective antigen delivery and immune stimulation in nasal mucosa determine the success of
mucosal immunity. Here, an oil-in-ionic liquid (o/IL) nanoemulsion formulated with choline …

Salivary polyreactive antibodies and Haemophilus influenzae are associated with respiratory infection severity in young children with recurrent respiratory infections

MH Koenen… - European …, 2024 - publications.ersnet.org
Background Recurrent respiratory tract infections (rRTIs) are a common reason for
immunodiagnostic testing in children, which relies on serum antibody level measurements …

Advances in the prophylaxis of respiratory infections by the nasal and the oromucosal route: relevance to the fight with the SARS-CoV-2 pandemic

N Ivanova, Y Sotirova, G Gavrailov, K Nikolova… - Pharmaceutics, 2022 - mdpi.com
In this time of COVID-19 pandemic, the strategies for prevention of the infection are a
primary concern. Looking more globally on the subject and acknowledging the high degree …

Autoimmunity: a new focus on nasal polyps

J Huang, Y Xu - International Journal of Molecular Sciences, 2023 - mdpi.com
Chronic rhinosinusitis with nasal polyps (CRSwNP) has long been considered a benign,
chronic inflammatory, and hyperplastic disease. Recent studies have shown that …

Monitoring the Cascade of Monocyte-Derived Macrophages to Influenza Virus Infection in Human Alveolus Chips

C Wang, S Liu, C Li, Z Wang, R Ming… - ACS Applied Materials …, 2024 - ACS Publications
Respiratory viruses ravage the world and seriously threaten people's health. Despite intense
research efforts, the immune mechanism underlying respiratory virus-induced acute lung …

Preliminary study on molecular mechanism of COVID-19 intervention by Polygonum cuspidatum through computer bioinformatics

T Liu, R Han, Y Yan - Medicine, 2024 - journals.lww.com
To explore the mechanism of action of Polygonum cuspidatum in intervening in coronavirus
disease 2019 using a network pharmacology approach and to preliminarily elucidate its …

The protective effect of intranasal immunization with influenza virus recombinant adenovirus vaccine on mucosal and systemic immune response

YB Lian, MJ Hu, TK Guo, YL Yang, RR Zhang… - International …, 2024 - Elsevier
Influenza virus is a kind of virus that poses several hazards of animal and human health.
Therefore, it is important to develop an effective vaccine to prevent influenza. To this end we …