Antibiotics are often used in human and veterinary medicine for the treatment of bacterial
diseases. However, extensive use of antibiotics in agriculture can result in the contamination …

Aptamers that undergo conformational changes upon small-molecule recognition have been
shown to gate the ionic flux through nanopores by rearranging the charge density within the …

Coronary heart disease (CHD) is a dangerous condition that cannot be completely cured.
Accurate detection of early coronary artery disease can assist physicians in treating patients …

Introduction Aptamers refer to short ssDNA/RNA sequences that target small molecules,
proteins, or cells. Aptamers have significantly advanced diagnostic applications, including …

Protamines are arginine-rich proteins that condense DNA in sperm. Despite their importance
in reproduction, information on protamine structure is scarce. We, therefore, used molecular …

Rosemary represents an important medicinal plant that has been attributed with various
health-promoting properties, especially antioxidative, anti-inflammatory, and …

Nonsense correlations frequently develop between independent random variables that
evolve with time. Therefore, it is not surprising that they appear between the components of …

Understanding aptamer–ligand interactions is necessary to rationally design aptamer-based
systems. Commonly used in silico tools have proven to be accurate to predict RNA and DNA …

Cancer's global impact necessitates innovative and less toxic treatments.
Thiosemicarbazones (TSCs), adaptable metal chelators, offer such potential. In this study …

Guanidinium ion is a toxic cellular metabolite. The ykkC-III riboswitch, an mRNA stretch,
regulates the gene expression by undergoing a conformational change in response to the …